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  1. Methylation of Promoters of microRNAs and their Host Genes in Myelodysplastic Syndromes.

    ... hematopoietic malignancies characterized by ineffective hematopoiesis . Recently, we identified MDS-associated microRNAs (miRNAs) ...

    Research Article last updated 05/14/2013 - 2:58pm.

  2. Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

    Journal Title:  N Engl J Med Primary Author:  Mufti GJ Author(s):  Mufti GJ, ...

    Research Article last updated 12/07/2015 - 1:36pm.

  3. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

    ... characterized by variable cytopenias and ineffective hematopoiesis . Hematopoietic stem cells (HSCs) and myeloid ... by increasing their frequency at the expense of normal hematopoiesis, that the loss of MDS myeloid progenitors by programmed cell ...

    Research Article last updated 03/05/2013 - 9:20am.

  4. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes

    ... clonal hematopoietic stem cell disorders of ineffective hematopoiesis that characteristically demonstrate peripheral blood ...

    Research Article last updated 02/04/2014 - 2:01pm.

  5. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

    ... Hematopoiesis in health and disease results from complex interactions ...

    Research Article last updated 04/09/2014 - 9:39am.

  6. Azacitidine in the management of patients with myelodysplastic syndromes.

    ... hematopoeitic disorders characterized by ineffective hematopoiesis and potential transformation to acute myeloid leukemia (AML). ...

    Research Article last updated 05/14/2013 - 2:48pm.

  7. Diagnosis and Treatment of Aplastic Anemia

    ... With the recent appreciation of frequent clonal hematopoiesis in AA patients and with the growing use of next-generation ...

    Research Article last updated 01/30/2018 - 10:53am.

  8. Molecular pathogenesis of myelodysplastic syndromes

    ... hematologic disorders characterized by inefficient hematopoiesis , hypercellular bone marrow , dysplasia of ...

    Research Article last updated 05/22/2014 - 10:05am.

  9. Risk and timing of cardiovascular death among patients with myelodysplastic syndromes

    ... with progression to leukemia and poor survival. Clonal hematopoiesis in people without an MDS diagnosis carries an increased risk ... between patients with MDS and those with non-MDS clonal hematopoiesis; therefore, we evaluated the risk of cardiovascular death among ...

    Research Article last updated 11/03/2017 - 10:36am.

  10. Progress in Myelodysplastic Syndromes: Clinicopathologic Correlations and Immune Checkpoints

    ... a group of clonal neoplasms characterized by ineffective hematopoiesis . Hypomethylating agent (HMA) therapy is one of the mainstays ... MDS, the immune system has a pivotal role in modulation of hematopoiesis and clonal expansion. In neoplastic conditions, immune checkpoint ...

    Research Article last updated 09/11/2017 - 8:59am.