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  1. Eltrombopag and improved hematopoiesis in refractory aplastic anemia

    ... bone marrow biopsies showed normalization of trilineage hematopoiesis in patients who had a response, without increased ...

    Research Article last updated 07/31/2012 - 2:24pm.

  2. Foundation Update - August 2017

    ... by NIH to study the effects of DNA damage accrual in hematopoiesis . In the last few years, Dr. Batista has built on his initial ...

    Article last updated 09/05/2017 - 10:53am.

  3. Marrow protein may be key to SCT success

    ... cells, including immune cells, in a process known as hematopoiesis . A new study led by University of Pennsylvania and ...

    Article last updated 08/29/2017 - 11:18am.

  4. Top honor goes to AAMDSIF Medical Advisor

    ... myeloma. Recent studies have characterized clonal hematopoiesis and its contribution to both hematologic malignancies and ... Award, and the International Society for Experimental Hematopoiesis Till and McCullough Award. “The Society is honored ...

    Article last updated 08/29/2017 - 7:54am.

  5. Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes

    ... are blood disorders characterized by ineffective hematopoiesis and progressive marrow failure that can transform into acute ... founder clones are not eliminated and continue to drive hematopoiesis even in complete responders. Bone ...

    Research Article last updated 08/03/2017 - 9:16am.

  6. Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

    ... that are characterized by defective bone marrow hematopoiesis and by the occurrence of intramedullary apoptosis . ... that the dysregulation of these molecules leads to abnormal hematopoiesis, unbalanced cell death and proliferation in patients' bone marrow ...

    Research Article last updated 06/21/2017 - 11:10am.

  7. Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

    ...

    Research Article last updated 12/07/2015 - 1:36pm.

  8. Methylation of Promoters of microRNAs and their Host Genes in Myelodysplastic Syndromes.

    ... hematopoietic malignancies characterized by ineffective hematopoiesis . Recently, we identified MDS-associated microRNAs (miRNAs) ...

    Research Article last updated 05/14/2013 - 2:58pm.

  9. An exploratory clinical trial of bortezomib in patients with lower risk myelodysplastic syndromes

    ... syndromes (MDSs) are characterized by ineffective hematopoiesis and an increased risk of transformation. Few effective ...

    Research Article last updated 05/02/2017 - 10:33am.

  10. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

    ... characterized by variable cytopenias and ineffective hematopoiesis . Hematopoietic stem cells (HSCs) and myeloid ... by increasing their frequency at the expense of normal hematopoiesis, that the loss of MDS myeloid progenitors by programmed cell ...

    Research Article last updated 03/05/2013 - 9:20am.