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  1. Filgrastim, Cladribine, Cytarabine and Mitoxantrone With or Without Sorafenib Tosylate in Treating Patients With Newly-Diagnosed, High-Risk Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... filgrastim ( granulocyte colony-stimulating factor [G-CSF]), cladribine, cytarabine, mitoxantrone hydrochloride, when given ... hydrochloride work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from ...

    Clinical Trial last updated 04/29/2016 - 1:03pm.

  2. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may also stop the patient's immune system from ... (GI) physician; unless there is a clear precipitating factor (such as an azole, methotrexate, Bactrim or another drug); if the GI ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  3. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may also stop the patient's immune system from ... (GI) physician unless there is a clear precipitating factor (such as an azole, methotrexate, Bactrim or another drug); if the GI ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  4. Supportive Care

    ... chelation therapy to treat iron overload Growth factors Antibiotics Blood transfusions involve putting ... replace immunosuppressive therapy. Red cell growth factor is called erythropoietin or EPO for short. It is a ...

    Page last updated 08/29/2013 - 4:20pm.

  5. Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

    ... hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from ... Methionyl Human Granulocyte Colony Stimulating Factor rG-CSF Tbo-filgrastim Tevagrastim Other: Laboratory Biomarker ...

    Clinical Trial last updated 04/28/2016 - 1:17pm.

  6. Total Marrow Irradiation for Refractory Acute Leukemia

    ... or hematopoietic stem cell transplant helps stop the growth of cancer cells. It may also stop the patient's immune system from ... Biological: Granulocyte colony-stimulating factor 5 mcg/kg/day intravenous or subcutaneous based on body weight ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  7. Infections in myelodysplastic syndromes: a review

    ... of WBC) is considered to be the most important predisposing factor to infections, several other immune defects involving B cells, T cells ... counts have been tried in neutropenic MDS patients with growth factors such as G-CSF or GM-CSF with results inconclusive at best. G-CSF ...

    Research Review last updated 05/02/2016 - 9:28am.

  8. Bone Marrow and Stem Cell Transplantation

    ... stem cells (PBSC) – The donor is given a white cell growth factor that increases the production of white blood cells and also ...

    Page last updated 09/30/2014 - 11:47am.

  9. Transplantation

     

    Page last updated 01/20/2015 - 4:45pm.

  10. PNH - Basics

    ... of mature PNH red blood cells. Some doctors believe this growth happens because people with PNH have bone marrow that is weaker than ... Having aplastic anemia is the only known risk factor for developing PNH. More than 10 out of every 100 people with aplastic ...

    Topic section last updated 04/05/2016 - 4:02pm.