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  1. Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

    ... is a novel fusion protein that blocks transforming growth factor beta (TGF β) superfamily inhibitors of erythropoiesis, giving rise ...

    Research Article last updated 09/18/2017 - 1:38pm.

  2. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... at 3 and 6 months, respectively. While additional growth factor interventions led to faster count recovery, there were no ...

    Research Article last updated 09/13/2017 - 7:40am.

  3. Promising trial results for lower-risk MDS drug

    ... is a novel fusion protein that blocks transforming growth factor beta (TGF β) superfamily inhibitors of erythropoiesis, giving rise ...

    Article last updated 09/07/2017 - 11:08am.

  4. Making Progress for Myelodysplastic Syndromes

    ... treatment because in CMML they have oversensitivity to a growth factor called GM-CSF, where Jakafi will target. We conducted the first ...

    Article last updated 07/26/2017 - 10:25am.

  5. Treatment of low-risk myelodysplastic syndromes

    ... neutropenia is targeted symptomatically with growth factor supportive care , the immunosuppressive treatments are ...

    Research Article last updated 01/26/2017 - 10:42am.

  6. High levels of vascular endothelial growth factor protein expression are associated with an increased risk of transfusion dependence in myelodysplastic syndromes

    ... the prognostic significance of vascular endothelial growth factor (VEGF) protein expression in 79 bone marrow biopsy specimens ...

    Research Article last updated 03/05/2013 - 9:11am.

  7. Growth Factors

    ... Red Cell Growth Factor Red cell growth factor is ...

    Topic section last updated 04/06/2016 - 12:37pm.

  8. Eltrombopag Added to IST Yields Encouraging Results

    ... cells with a drug that mimics the actions of a natural growth substance for marrow stem cells while suppressing the immune system ... burden by giving them a drug known to be a growth factor for platelets. To our surprise, we observed not only an improvement ...

    Interview last updated 05/24/2017 - 7:44am.

  9. Danielle Townsley, MD, MSc

    ... failure syndromes and the use of eltrombopag, a blood growth factor to treat aplastic anemia . She also studies familial causes ...

    Bio last updated 05/24/2017 - 8:30am.

  10. The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes.

    ... of the spliceosomal mutations on RNA splicing and cell growth have been evaluated only in a limited context to date, however, and the ...

    Research Article last updated 10/22/2013 - 3:41pm.