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  1. Cutting the cord from myelodysplastic syndromes: chronic myelomonocytic leukemia-specific biology and management strategies

    ... with MDS and critical dependence of CMML cells on granulocyte -macrophage colony-stimulating factor signaling. In addition, ...

    Research Article last updated 03/02/2015 - 1:22pm.

  2. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution.

    ... blood counts and persisted an average of 2 months. Granulocyte transfusions for uncontrolled infection were required in 5, ...

    Research Article last updated 10/07/2014 - 8:33am.

  3. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

    ... blood counts and persisted an average of 2 months. Granulocyte transfusions for uncontrolled infection were required in 5, ...

    Research Article last updated 09/24/2014 - 10:17am.

  4. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... MSC infusion. Stem cell grafts used a combination of granulocyte colony-stimulating factor (G-CSF)-primed bone marrow ...

    Research Article last updated 04/09/2014 - 9:16am.

  5. Baseline characteristics and disease burden in patients in the international paroxysmal nocturnal hemoglobinuria registry

    ... enrolled. Median disease duration was 4.6 years. Median granulocyte paroxysmal nocturnal hemoglobinuria clone size was 68.1% ...

    Research Article last updated 03/06/2014 - 11:30am.

  6. A prospective multicenter study of paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure.

    ... flow cytometry detection of PNH clones. RESULTS: Granulocyte PNH clones ≥ 1% were detected in 199 of all 5,398 patients ...

    Research Article last updated 11/21/2013 - 11:54am.

  7. A Prospective Multicenter Study of Paroxysmal Nocturnal Hemoglobinuria Cells in Patients with Bone Marrow Failure.

    ... flow cytometry detection of PNH clones. Results: Granulocyte PNH clones ≥ 1% were detected in 199 of all 5398 patients ...

    Research Article last updated 10/22/2013 - 3:42pm.

  8. Rabbit Antithymocyte Globulin Treatment in Childhood Acquired Severe Aplastic Anemia.

    ... were treated with rabbit ATG, cyclosporine , and granulocyte colony stimulating factor (GCSF) between 2006 and 2012. Fifteen ...

    Research Article last updated 06/20/2013 - 10:32am.

  9. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

    ... cells in MDS. We identify a recurrent loss of granulocyte -macrophage progenitors (GMPs) in the bone marrow of low ...

    Research Article last updated 03/05/2013 - 9:20am.

  10. Revisiting use of growth factors in myelodysplastic syndromes

    ... advent of use of hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) and recombinant ...

    Research Article last updated 07/31/2012 - 12:57pm.