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  1. Preventing Stem Cell Transplant Complications With a Blood Separator Machine

    ... and more effective. One complication of transplants is graft-versus-host disease (GVHD) . This complication happens when certain white blood cells ...

    Clinical Trial last updated 05/23/2016 - 10:57am.

  2. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... II. To determine the incidence and severity of graft-versus-host disease (GVHD) in patients undergoing treated on the Thomas Jefferson ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  3. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... . Removing T-cells may help stop a side effect called Graft-Versus-Host Disease (GVHD) . Some studies have been done with CliniMACS, but the Food ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  4. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... tumor cells to NK cytotoxicity and protect against graft-versus-host disease (GVHD) , and (3) eliminating mycophenolate mofetil from the ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  5. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... HLA matched related and unrelated donors. However, graft-versus-host disease (GvHD) continues to be a problem and is associated with significant ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  6. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... mofetil is safe and effective in preventing severe graft-versus-host disease (GVHD) in most patients with hematologic malignancies undergoing ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  7. T-cell Depleted Alternative Donor Transplantation

    ... using the CliniMACS® device to prevent severe acute graft-versus-host disease (GVHD) in patients receiving a stem cell transplant from an ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  8. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... III. To determine the incidence and severity of graft-versus-host disease (GVHD) in patients undergoing treated on the TJU RIC 2 step ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  9. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... related mortality and the rates of moderate and severe graft-versus-host disease (GvHD) at day 100. The investigators will describe event-free, and ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  10. Bone Marrow Transplant

    ... transplant works depends on many things, such as: The disease being treated The stage of the disease The patient's age and ... These problems can include serious infections and graft-versus-host disease (GVHD) , in which the transplanted cells attack ...

    Topic section last updated 03/29/2016 - 7:27pm.