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  1. REVERSE 1 INCB 18424-271

    ... for the Treatment of Steroid- Refractory Acute Graft-Versus-Host Disease - The purpose of this study is to assess the efficacy of ruxolitinib in ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  2. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... Purpose:  Acute Graft-versus-Host-Disease (GVHD) is an important cause of morbidity and mortality after ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  3. A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation

    ... Bone Marrow Disease(s):  acute myeloid leukemia (AML) ... at the time of screening, or with clinically significant graft-versus-host disease (GVHD) . (The use of a stable dose of oral ...

    Clinical Trial last updated 02/22/2017 - 11:21am.

  4. A Phase II Trial of CD24Fc for Prevention of Acute Graft-versus-Host Disease Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

    ... the MTD (Maximum Tolerated Dose) of CD24Fc for acute GVHD (Graft Versus Host Disease) prophylaxis. Status:  ...

    Clinical Trial last updated 04/29/2016 - 11:03am.

  5. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... randomized phase III trial studies how well graft-vs-host disease (GVHD) prophylaxis works in treating patients with hematologic malignancies ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.

  6. Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Hematologic Malignancies Undergoing Donor Peripheral Blood Stem Cell Transplant

    ... and mycophenolate mofetil works in preventing graft-vs-host disease (GVHD) in patients with hematologic malignancies undergoing donor peripheral ...

    Clinical Trial last updated 04/28/2016 - 12:07pm.

  7. Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

    ... donor atorvastatin treatment works in preventing severe graft-versus-host disease (GVHD) after nonmyeloablative peripheral blood stem cell (PBSC) ...

    Clinical Trial last updated 05/03/2016 - 9:44am.

  8. Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis

    ... in the post transplant setting to prevent onset of acute graft-versus-host disease (GVHD) . The primary objective is to determine the incidence of ...

    Clinical Trial last updated 04/27/2016 - 9:38am.

  9. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... Purpose:  Graft-versus-host disease (GVHD) is a condition that results from a reaction of transplanted ...

    Clinical Trial last updated 04/27/2016 - 8:55am.

  10. Clinical Trials Report for April 2016

    ... in the post transplant setting to prevent onset of acute graft-versus-host disease (GVHD) . The primary objective is to determine the incidence of ...

    Page last updated 08/10/2016 - 11:00am.