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  1. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... Purpose:  Graft-versus-host disease (GVHD) is a condition that results from a reaction of transplanted ...

    Clinical Trial last updated 04/27/2016 - 8:55am.

  2. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... blood stem cell transplant works in preventing graft-versus-host disease in younger patients with high risk hematologic malignancies. Giving ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  3. Allo HSCT Using RIC for Hematological Diseases

    ... The primary objective is to evaluate rates of acute graft-versus-host disease (GVHD) grades II-IV and chronic GVHD with an updated GVHD prophylaxis of ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  4. TBI Dose De-escalation for Fanconi Anemia

    ... engraftment , whichever day is later, if no acute graft-versus-host disease (GVHD) . 4) If the subject is receiving bone marrow or ...

    Clinical Trial last updated 04/28/2016 - 9:06am.

  5. T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

    ... to participate in this study because treatment of their disease requires them to receive a stem cell transplant . Stem cells ... there is typically an increased risk of developing graft-versus-host disease (GVHD) , a high rate of transplant failure, and a ...

    Clinical Trial last updated 04/28/2016 - 12:15pm.

  6. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... HLA matched related and unrelated donors. However, graft-versus-host disease (GvHD) continues to be a problem and is associated with significant ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  7. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... related mortality and the rates of moderate and severe graft-versus-host disease (GvHD) at day 100. The investigators will describe event-free, and ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  8. Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

    ... Secondary To evaluate the incidence of acute graft-versus-host disease (GVHD) and chronic GVHD in patients treated with this regimen. ...

    Clinical Trial last updated 04/28/2016 - 8:53am.

  9. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD) . This is less likely when the recipient and donor have ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  10. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... 10 patients using sirolimus/Mycophenolate mofetil (MMF) graft-versus-host disease (GVHD) prophylaxis to gain further safety information and to ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.