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  1. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... had an increased cumulative incidence of grades II-IV acute graft-versus-host disease (aGVHD) (30.3 vs. 1.5%, P < 0.001), grades III-IV aGVHD (10.1 vs. ...

    Research Article last updated 02/03/2017 - 9:40am.

  2. Recent developments in bone marrow transplants

    ... prior to allogeneic HSCT significantly increased risk for graft-versus-host disease (GVHD)–related mortality in adults with T-cell leukemia/lymphoma. ...

    Article last updated 11/16/2016 - 2:56pm.

  3. Major news in BMT with half-match donors

    ... syndrome, also called pre-leukemia or MDS. By 2014, his disease had progressed to acute myeloid leukemia (AML), which affects more than ... the best choice,” Dr. Vusirikala said. “But the risk of graft-versus-host-disease (GvHD) following a transplant using a half-match is ...

    Article last updated 06/14/2016 - 3:02pm.

  4. Allogeneic transplantation for aplastic anemia

    ... higher than after HLA-matched sibling transplantation. Graft-versus-host disease (GVHD) is higher; GVHD can lead to significant morbidity and ...

    Research Article last updated 07/03/2012 - 2:57pm.

  5. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... two calcineurin inhibitor (CNI)-free strategies for Graft-versus-Host Disease (GVHD) prophylaxis to standard tacrolimus and methotrexate ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.

  6. ALLOGENEIC STEM CELL TRANSPLANTATION (HSCT) FOR ADULTS WITH MYELODYSPLASTIC SYNDROMES (MDS): RELEVANCE OF PRE-TRANSPLANT DISEASE STATUS.

    ... 53 patients (56%) had relapsed/ refractory disease. The cumulative incidence of grades II-IV acute graft-versus-host disease (GVHD) and chronic GVHD were 33% (21%-45%, 95% ...

    Research Article last updated 06/28/2013 - 1:28pm.

  7. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... mesenchymal stem cells (MSC) affected graft failure and graft-versus-host disease (GVHD) in patients with severe aplastic anemia (SAA). ...

    Research Article last updated 04/09/2014 - 9:16am.

  8. Hematopoietic stem cell transplantation with umbilical cord multipotent stromal cell infusion for the treatment of aplastic anemia-a single-center experience.

    ... Fludarabine -based conditioning was conducted, and graft-versus-host disease prophylaxis containing cyclosporine A, methotrexate and ...

    Research Article last updated 07/09/2013 - 2:48pm.

  9. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... by allele-level typing) affected hematopoietic recovery, graft-versus-host disease (GVHD) , or overall survival (OS). In multivariate analysis, ...

    Research Article last updated 06/15/2012 - 2:55pm.

  10. Alternative donor transplantation for aplastic anemia.

    ... risks of graft failure, regimen-related toxicity, and graft-versus-host disease (GVHD) . Despite the more than 14 million adults registered with ...

    Research Article last updated 10/11/2011 - 5:58pm.