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  1. Microarray-based comparative genomic hybridization of cancer targets reveals novel, recurrent genetic aberrations in the myelodysplastic syndromes

    ... by microarray-based comparative genomic hybridization (aCGH) in all samples (range 1-31, median 5). In 28 of 35 samples (80%), aCGH revealed new cytogenetic aberrations not seen by karyotype or fluorescence in situ hybridization ( FISH ). Furthermore, 132 cryptic ...

    Research Article last updated 01/09/2012 - 11:10am.

  2. Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia

    ... , a second course of immunosuppression is successful in only one-fourth to one-third of cases. METHODS: We conducted a ... responses at 6 months. We failed to demonstrate by fluorescence in situ hybridization or variable number tandem repeat any ...

    Research Article last updated 12/09/2015 - 1:27pm.

  3. Investigation of 305 patients with myelodysplastic syndromes and 20q deletion for associated cytogenetic and molecular genetic lesions and their prognostic impact

    ... In patients with myelodysplastic syndromes (MDS), sole 20q deletion ... and chromosome banding analysis (CBA), subsets by fluorescence in situ hybridization , molecular mutation screening, ...

    Research Article last updated 01/08/2014 - 8:30am.

  4. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes

    ... metaphase cytogenetics and judicious use of fluorescence in situ hybridization play central roles in the contemporary diagnosis and ...

    Research Article last updated 02/04/2014 - 2:01pm.

  5. Telomere length in myelodysplastic syndromes

    ... age-matched controls (n = 63). Relative TL was measured in PBLs and saliva by quantitative polymerase chain reaction (PCR) and in CD15+ and CD19+ cells by flow cytometry - fluorescence in situ hybridization (flow- FISH ). Human telomerase ...

    Research Article last updated 10/11/2011 - 5:58pm.