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  1. Proposed score for survival of patients with myelodysplastic syndromes.

    ... RESULTS: By multivariate analysis, IPSS, ferritin , age and comorbidities were found to be independent predictive ... other, we established a novel survival score employing IPSS, ferritin (< 900 ng/mL = 0; ≥ 900 ng/mL = 1), age (< 70 years = 0; 70-79 years ...

    Research Article last updated 10/22/2013 - 2:50pm.

  2. The Evaluation of iron overload through hepcidin level and its related factors in myelodysplastic syndromes.

    ... factor 15 and twisted gastrulation 1. Serum ferritin (SF), C-reactive protein (CRP), and erythropoietin were ... correlation (r = 0.582, P < 0.001) to hepcidin than serum ferritin, by stepwise regression. C-reactive protein and LIC seemed to be the ...

    Research Article last updated 05/14/2013 - 3:00pm.

  3. Iron status and treatment modalities in transfusion-dependent patients with myelodysplastic syndromes.

    ... than 50 units since their MDS diagnosis. Medium serum ferritin was 1,550 μg/L. Ninety patients (46.6%) received iron ... judgment with the generally accepted guidelines of a serum ferritin level >1,000 μg/L and/or two or more RBC transfusions per month for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Efficacy and safety of deferasirox in myelodysplastic syndromes

    ... deferasirox , has been shown to reduce serum ferritin levels in chelation naïve and pre-treated patients and to reduce ...

    Research Article last updated 03/05/2013 - 9:15am.

  5. Impact of iron overload in myelodysplastic syndromes.

    ... addition, in patients with lower-risk MDS, a high serum ferritin level has been associated with an increased risk of leukaemic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: safety, efficacy, and unexpected laboratory phenomena

    ... transfusion independent. A significant increase in ferritin levels from a median of 104 μg/l before to a median of 528 μg/l ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Adequate iron chelation therapy for at least six months improves survival in transfusion-dependent patients with lower risk myelodysplastic syndromes

    ... chelation rate was 63% but 88% among patients with serum ferritin ≥1000μg/L. Of the 80 chelated patients, 70% were chelated ...

    Research Article last updated 07/29/2014 - 12:11pm.

  8. Iron overload in myelodysplastic syndromes: diagnosis and management.

    ... reduces iron load as measured by changes in serum ferritin and may prolong overall survival. Iron chelation strategies ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Revised International Prognostic Scoring System (IPSS-R) for myelodysplastic syndromes

    ... in the IPSS. Patient age, performance status, serum ferritin and LDH were significant additive features for survival but not ...

    Research Article last updated 07/29/2014 - 8:54am.

  10. Hypoalbuminemia is an independent prognostic factor for overall survival in myelodysplastic syndromes

    ... co-variate for OS after adjustment for IPSS, age, serum ferritin , and transfusion dependence (hazard ratio = 0.8; 95% CI 0.6-0.9; P ...

    Research Article last updated 11/05/2012 - 9:05am.