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  1. Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome

    ... in prolonged neutropenia and failure of engraftment which contributes to infection and transplant related mortality ... blood CD34+ cells from a related donor might promote rapid engraftment and reduce TRM secondary to prolonged neutropenia associated with ...

    Clinical Trial last updated 04/25/2016 - 2:18pm.

  2. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... transplants are still associated with risks such as engraftment failure and graft versus host disease (GVHD). However, ... risk. With multiple transfusions, the risk of failure of engraftment may increase when a stem cell transplant is finally performed. ...

    Interview last updated 11/28/2016 - 2:58pm.

  3. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... as well as the rates of hematopoietic recovery and donor engraftment and study comprehensively immune reconstitution following ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  4. T-cell Depleted Alternative Donor Transplantation

    ... donor. The secondary objectives include evaluation of engraftment , immune recovery, and post-transplant infections. Patients ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  5. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... conditioning and haplo-cord transplant results in fast engraftment of neutrophils and platelets, low incidences of acute and ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  6. Gene Therapy for Fanconi Anemia

    ... if infusion of FANCA gene-modified cells will result in engraftment and improvement in blood counts in FA patients. OUTLINE: ...

    Clinical Trial last updated 04/28/2016 - 9:03am.

  7. Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

    ... Determine whether the incidence of neutrophil engraftment is acceptable in high-risk patients with Fanconi's anemia ...

    Clinical Trial last updated 04/28/2016 - 8:49am.

  8. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... on the TJU RIC 2 step approach. IV. To evaluate engraftment rates and lymphoid reconstitution in patients treated on the ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  9. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... how often subjects had complications of GVHD and engraftment failure. People with aplastic anemia who have ...

    Clinical Trial last updated 04/21/2016 - 1:19pm.

  10. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... (TJU) RIC 2 step approach. III. To evaluate engraftment rates and lymphoid reconstitution in patients treated on the ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.