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  1. REVERSE 1 INCB 18424-271

    ... of corticosteroids is achieved. • Evidence of myeloid engraftment (eg, absolute neutrophil count ≥ 1.0 × 10^9/L for 3 ... is allowed. Evidence of platelet engraftment (ie, platelets ≥ 20 × 10^9/L) ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  2. TBI Dose De-escalation for Fanconi Anemia

    ... mofetil (MMF) through day +30 or for 7 days after engraftment , whichever day is later, if no acute graft-versus-host ... beginning on day -3 through day +30 or for 7 days after engraftment, whichever day is later, if no acute graft-versus-host disease ...

    Clinical Trial last updated 04/28/2016 - 9:06am.

  3. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... results thus far. Our long term leukocyte engraftment rate is 85-90% with the same disease-free survival. None of the ... limitation is the significant delay in donor red cell engraftment in one recipient who had pre-existing allo-antibody to donor red ...

    Clinical Trial last updated 04/28/2016 - 9:09am.

  4. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... transplants are still associated with risks such as engraftment failure and graft versus host disease (GVHD). However, ... risk. With multiple transfusions, the risk of failure of engraftment may increase when a stem cell transplant is finally performed. ...

    Interview last updated 11/28/2016 - 2:58pm.

  5. Cord Blood Transplant

    ... early skepticism in adults because of concerns about the engraftment potential of the relatively limited number of stem cells. The ... recipients from the NYBC revealed a cumulative rate of engraftment of 81% by day 42 for PMNs. and 85% by day 180 for platelets. ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  6. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... regimen-related toxicity while maintaining better engraftment , this study is to evaluate the effectiveness and safety of ... survival probability at 3 months, 6 months and 1 year. Engraftment at 3 months, 6 months and 1 year Incidence of graft versus host ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  7. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... the time to neutrophil and platelet engraftment , to determine the time to immune reconstitution (including ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.

  8. Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

    ... stem cell transplant to facilitate engraftment and the safety of AP1903 on day 7 to prevent GVHD. ...

    Clinical Trial last updated 06/13/2016 - 1:54pm.

  9. New York Blood Center National Cord Blood Program

    ... to assess cord blood myeloid and platelet engraftment , transplant related mortality, overall survival, graft vs. host ...

    Clinical Trial last updated 06/13/2016 - 1:43pm.

  10. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... B cell depletion to determine efficacy as determined by engraftment and GVHD, and one year leukemia free survival. ...

    Clinical Trial last updated 06/06/2016 - 3:10pm.