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  1. Engraftment of heavily transfused patients with severe aplastic anemia with a fludarabine-based regimen

    ... [-5 to -2]). Altogether, 81 patients indicated initial engraftment , whereas two cases showed primary graft failure. And four of ... disease (50/83; 60.2%), in total, 77 patients showed durable engraftment and transfusion independence , and 64 are alive at a median ...

    Research Article last updated 03/05/2013 - 8:04am.

  2. New study on SCT therapy for SAA, MDS patients

    ... Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Imrpove Transplant Outcome, is a Phase ½ trial in which the primary endpoint is prompt and durable cord engraftment. "The study, announced today, represents a significant ...

    Article last updated 08/22/2017 - 9:41am.

  3. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... the efficacy and safety of sitagliptin in enhancing engraftment following umbilical cord blood transplantation (recovery of ...

    Clinical Trial last updated 06/06/2016 - 3:37pm.

  4. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... the efficacy and safety of sitagliptin in enhancing engraftment following umbilical cord blood transplantation (recovery of ...

    Clinical Trial last updated 06/03/2016 - 2:54pm.

  5. Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation.

    ... ×, P<1e-6). Of all the outcome parameters evaluated ( engraftment , rejection/graft failure, GvHD, TRM, OS), high F-araA AUC ...

    Research Article last updated 05/22/2017 - 10:32am.

  6. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    Journal Title:  Haematologica Primary Author:  Gerull S Author(s):  Gerull S,...

    Research Article last updated 08/05/2013 - 9:44am.

  7. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    Journal Title:  Biol Blood Marrow Transplant Primary Author:  Battiwalla M Author(s):  ...

    Research Article last updated 06/15/2012 - 2:55pm.

  8. Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results

    ... out of 44 patients, who died early before hematopoietic engraftment , were not assessed. Evaluable patients (97.6%; 40/41) achieved ... sustained full donor chimerism. The median time for myeloid engraftment was 12 days (range 8-21 days) and for platelet engraftment ...

    Research Article last updated 02/01/2017 - 12:30pm.

  9. Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

    ... Have identified a back-up cell source in case of engraftment failure. The source can be autologous, related or unrelated. ...

    Clinical Trial last updated 06/06/2016 - 12:58pm.

  10. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... donors (MRDs) for HSCT. The median times for myeloid engraftment in the HID and MRD cohorts were 12 (range, 9-20) and 11 (range, ... status pre-SCT. We did not observe differences in primary engraftment and survival outcomes by donor type. CONCLUSIONS: ...

    Research Article last updated 02/03/2017 - 9:40am.