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  1. Engraftment of heavily transfused patients with severe aplastic anemia with a fludarabine-based regimen

    ... [-5 to -2]). Altogether, 81 patients indicated initial engraftment , whereas two cases showed primary graft failure. And four of ... disease (50/83; 60.2%), in total, 77 patients showed durable engraftment and transfusion independence , and 64 are alive at a median ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    Journal Title:  Haematologica Primary Author:  Gerull S Author(s):  Gerull S,...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    Journal Title:  Biol Blood Marrow Transplant Primary Author:  Battiwalla M Author(s):  ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia

    ... Among the 12 patients, 11 achieved neutrophil engraftment at a median of 10 days (range, 9 to 13 days) after HHCT. One patient failed to achieve primary engraftment, and two experienced graft rejection soon after engraftment. All ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Allogeneic stem cell transplantation using alemtuzumab-containing regimens in severe aplastic anemia.

    ... used to reduce graft-versus- host disease (GVHD) and aid engraftment after allogeneic haemopoietic stem cell transplant ... in SAA and show that it results in sustained haematological engraftment, a very low incidence of chronic GVHD without an increase in viral ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    ... those with severe fibrosis (n=39) and analyzed regarding engraftment , treatment-related mortality, relapse and survival. RESULTS: ... abnormal cytogenetics . The cumulative incidence of engraftment achieved at day +30 in non-fibrotic patients was 93% and was ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Hematopoietic stem cell transplantation with umbilical cord multipotent stromal cell infusion for the treatment of aplastic anemia-a single-center experience.

    ... monoclonal antibody was performed. Hematopoietic engraftment , the occurrence of graft-versus-host disease (GVHD) and ... were documented. RESULTS: All patients had rapid engraftment; mean time for neutrophil and platelet recovery was ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... cord were infused on day 1. Neutrophil engraftment was achieved in all 17 patients in a median time of 16 days (range 9-25 days). The median time of platelet engraftment was 22 days (range 9-95 days) in 16 patients. The cumulative ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Unrelated cord blood transplantation for newly diagnosed patients with severe acquired aplastic anemia using a reduced-intensity conditioning: high graft rejection, but good survival.

    ... as GVHD prophylaxis. Two patients were not evaluable for engraftment because of early death on day +21 and +22. Only one of the sixteen cases achieved engraftment, but experienced secondary graft failure 3 months post ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Comparison between Matched Related and Alternative Donors of Allogeneic Hematopoietic Stem Cells Transplanted into Adult Patients with Acquired Aplastic Anemia: Multivariate and Propensity Score-Matched Analysis.

    ... that age at alloHSCT of ≤31 years, MRD, successful engraftment , absence of acute graft-versus-host disease (aGVHD), and platelet engraftment at ≤21 days, were independent predictors of longer survival. In ...

    Research Article last updated 07/20/2018 - 5:14pm.