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  1. Antonio Maria Risitano, MD, PhD

    ... mechanism of hemolysis may emerge during eculizumab treatment; it can be designated as "C3-mediated extravascular ... possible explanations for the heterogeneity of response to eculizumab treatment, based on inherited factors. These studies were pivotal ...

    Bio last updated 10/20/2017 - 9:50am.

  2. Ricky Smith, Jr. Battles a One-Two Punch of Aplastic Anemia and PNH

    ... got the information he needed along with help obtaining eculizumab (Soliris®). “When I got that, things started to take a turn ...

    Patient Chronicle last updated 03/27/2017 - 1:21pm.

  3. Eculizumab

    ... (PNH) Eculizumab causes the complement system , a part of your immune ...

    Drug last updated 03/24/2016 - 12:32pm.

  4. Small-molecule Factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

    ... alternative pathway of complement that are treated with eculizumab , a humanized monoclonal antibody against the terminal complement component C5. Eculizumab must be administered intravenously, and moreover some patients with ...

    Research Article last updated 11/28/2016 - 11:42am.

  5. Thrombotic complications without evidence of hemolysis in paroxysmal nocturnal hemoglobinuria: is eculizumab indicated?

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    Research Article last updated 07/31/2012 - 12:44pm.

  6. Eculizumab treatment of paroxysmal nocturnal hemoglobinuria presenting as moyamoya syndrome in a 9-year-old male.

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    Research Article last updated 04/24/2012 - 2:57pm.

  7. Hemolytic anemia after eculizumab in paroxysmal nocturnal hemoglobinuria.

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    Research Article last updated 10/11/2011 - 5:58pm.

  8. Successful discontinuation of anticoagulation following eculizumab administration in paroxysmal nocturnal hemoglobinuria.

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    Research Article last updated 10/11/2011 - 5:58pm.

  9. Paroxysmal nocturnal hemoglobinuria and eculizumab.

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    Research Article last updated 10/11/2011 - 5:58pm.

  10. Resources to Help

    ... Assists patients who have been prescribed Solaris ( eculizumab ) by connecting them to alternate funding sources and by getting ...

    Topic section last updated 11/15/2017 - 2:31pm.