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  1. Resources to Help

    ... Assists patients who have been prescribed Solaris ( eculizumab ) by connecting them to alternate funding sources and by getting ...

    Topic section last updated 10/20/2017 - 10:23am.

  2. Eculizumab: a guide to its use in paroxysmal nocturnal hemoglobinuria

    ... The targeted terminal complement inhibitor eculizumab (Soliris) reduces intravascular hemolysis in patients ... reducing the requirement for packed red cell transfusions. Eculizumab is generally well tolerated in patients with PNH, although the risk ...

    Research Article last updated 07/30/2012 - 2:23pm.

  3. Special Precautions

    ... each case is different. PNH patients who are receiving eculizumab may be less likely to have hemolysis after receiving a flu ...

    Topic section last updated 09/08/2017 - 12:34pm.

  4. Small-molecule Factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

    ... alternative pathway of complement that are treated with eculizumab , a humanized monoclonal antibody against the terminal complement component C5. Eculizumab must be administered intravenously, and moreover some patients with ...

    Research Article last updated 11/28/2016 - 11:42am.

  5. Paroxysmal Nocturnal Hemoglobinuria (PNH)

    ... each case is different. PNH patients who are receiving eculizumab may be less likely to have hemolysis after receiving a flu shot. ...

    Page last updated 09/30/2017 - 11:34am.

  6. Eculizumab

    ... (PNH) Eculizumab causes the complement system , a part of your immune ...

    Drug last updated 03/24/2016 - 12:32pm.

  7. Thrombotic complications without evidence of hemolysis in paroxysmal nocturnal hemoglobinuria: is eculizumab indicated?

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    Research Article last updated 07/31/2012 - 12:44pm.

  8. Eculizumab treatment of paroxysmal nocturnal hemoglobinuria presenting as moyamoya syndrome in a 9-year-old male.

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    Research Article last updated 04/24/2012 - 2:57pm.

  9. Hemolytic anemia after eculizumab in paroxysmal nocturnal hemoglobinuria.

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    Research Article last updated 10/11/2011 - 5:58pm.

  10. Paroxysmal nocturnal hemoglobinuria and eculizumab.

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    Research Article last updated 10/11/2011 - 5:58pm.