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  1. Understanding the Compliment System and the PNH Clone

    ... a brief discussion about how complement inhibitors like Eculizumab can work to reduce or stop complement activation. As with all of ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  2. PNH 101: Understanding Diagnosis and Treatment

    ... experience. She also covers treatment options, including eculizumab , immunosuppressive drug therapy , stem cell ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  3. Interviews with the Experts: Hemolysis in PNH and Beyond

    ... this process is by blocking the action of complement.  Eculizumab (Soliris®) is an antibody to a component of the complement ... and prevents complement-induced red cells destruction.  Eculizumab has been studied in several clinical trials and is approved by the ...

    Interview last updated 08/31/2016 - 8:40am.

  4. Soliris

    Eculizumab (Soliris) is the only drug approved by the U.S. Food and Drug ... Children and Soliris If your child will be treated with eculizumab injection, your child should be vaccinated against Streptococcus ...

    Page last updated 06/29/2015 - 9:07am.

  5. What are the treatments for PNH?

    ... cyclosporine are the medicines typically used. Eculizumab (Soliris®):  The only drug approved by the U.S. Food and Drug ...

    FAQ last updated 03/15/2016 - 11:32pm.

  6. Dr. Heather Vega: Doctor Helps Determine Her Own Aplastic Anemia and PNH Diagnosis

    ... diagnosis. But after my diagnosis, I was placed on eculizumab (Soliris®) in a twice-monthly regimen. Although I remain ...

    Patient Chronicle last updated 06/27/2016 - 2:29pm.

  7. PNH Drug Information

    ... A ranesp eculizumab S oliris ...

    Page last updated 01/20/2015 - 4:56pm.

  8. Bone Marrow Transplant

    ... patients with low platelet counts while on  eculizumab should talk to their doctor about bone marrow transplant ...

    Topic section last updated 03/29/2016 - 7:27pm.

  9. Clinical Trial Basics

    ... (Exjade) lenalidomide (Revlimid) eculizumab (Soliris) azacitidine (Vidaza) eltrombopag ...

    Page last updated 03/29/2016 - 7:29pm.

  10. Special Issues for People with PNH

    ... be different. However, PNH patients who are receiving eculizumab may be less likely to have hemolysis after receiving a flu shot. ...

    Page last updated 01/20/2015 - 4:59pm.