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  1. Soliris

    Eculizumab (Soliris) is the only drug approved by the U.S. Food and Drug ... Children and Soliris If your child will be treated with eculizumab injection, your child should be vaccinated against Streptococcus ...

    Page last updated 06/29/2015 - 9:07am.

  2. AK579 (COBALT)

    ... Criteria:  Prior use of eculizumab (Soliris®) within 3 months of entry is prohibited Any other ...

    Clinical Trial last updated 09/14/2016 - 10:39am.

  3. PNH 101: Understanding Diagnosis and Treatment

    ... experience. She also covers treatment options, including eculizumab , immunosuppressive drug therapy , stem cell ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  4. PNH 101: Understanding Diagnosis and Treatment

    ... She also went over treatment options, including eculizumab , immunosuppressive drug therapy, stem cell transplantation, and ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  5. Understanding the Compliment System and the PNH Clone

    ... a brief discussion about how complement inhibitors like Eculizumab can work to reduce or stop complement activation. As with all of ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. Shahram Kordasti, MD, PhD

    ... of diagnosis and following therapy with C5 inhibitor ( Eculizumab ). PBMCs from these patients are stored as viable cells and being ... 5 PNH patients have been stained and analysed pre and post Eculizumab by the same method (10 samples) and the preliminary data suggest ...

    Grant Recipient last updated 08/02/2016 - 3:35pm.

  7. PNH Drug Information

    ... A ranesp eculizumab S oliris ...

    Page last updated 01/20/2015 - 4:56pm.

  8. What are the treatments for PNH?

    ... cyclosporine are the medicines typically used. Eculizumab (Soliris®):  The only drug approved by the U.S. Food and Drug ...

    FAQ last updated 03/15/2016 - 11:32pm.

  9. Interviews with the Experts: Hemolysis in PNH and Beyond

    ... this process is by blocking the action of complement.  Eculizumab (Soliris®) is an antibody to a component of the complement ... and prevents complement-induced red cells destruction.  Eculizumab has been studied in several clinical trials and is approved by the ...

    Interview last updated 08/31/2016 - 8:40am.

  10. Special Issues for People with PNH

    ... be different. However, PNH patients who are receiving eculizumab may be less likely to have hemolysis after receiving a flu shot. ...

    Page last updated 01/20/2015 - 4:59pm.