Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Katherine King, PhD

    ... deplete blood stem cells by forcing them to differentiate , effectively using them up prematurely. We identified a ... artificially turning on Batf2 in blood stem cells makes them differentiate prematurely. We are now in the process of antagonizing Batf2, and ...

    Grant Recipient last updated 07/07/2017 - 1:09pm.

  2. Stem and progenitor cell alterations in myelodysplastic syndromes

    ... markers such as IL1RAP, CD99, TIM3, CD123 have begun to differentiate MDS HSPCs from healthy counterparts. Overactivation of innate ...

    Research Article last updated 02/21/2017 - 10:17am.

  3. Research in making blood stem cells in the lab advances

    ... iPS cells) to chemical signals that direct stem cells to differentiate into specialized cells and tissues during normal embryonic ... it may not be a true blood stem cell. And once it starts to differentiate and make blood cells, you can't go back and study it—it's ...

    Article last updated 05/18/2017 - 7:18am.

  4. Pathogenesis of paroxysmal nocturnal hemoglobinuria

    ... mutant cells become GPI deficient, expand clonally and differentiate into all of the hematopoietic lineages. When GPI deficient ...

    Research Article last updated 11/02/2016 - 2:52pm.

  5. On the horizon: Man-made bone marrow

    ... minerals. Stem cells grown in this mineralized matrix differentiate into bone-building cells. The inner matrix houses donor stem ...

    Article last updated 05/09/2017 - 10:41am.

  6. Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia

    ... of infection and inflammation, IFNγ activates HSCs to differentiate and impairs their ability to self-renew, ultimately leading ...

    Research Article last updated 10/06/2016 - 9:44am.

  7. Stem cell origin of myelodysplastic syndromes

    ... stem cells, impairing their ability to proliferate and differentiate . Most importantly, aberrant stem cells can persist and ...

    Research Article last updated 01/08/2014 - 9:05am.

  8. Cynthia Dunbar, MD

    ... the mechanisms by which stem cells develop and differentiate into other cell types, particularly in relation to ...

    Bio last updated 03/11/2016 - 1:41pm.

  9. Jeffrey Pu, MD, PhD

    ... stem cells sit in bone marrow and are capable to differentiate into red blood cells, white blood cells, and platelets. ...

    Grant Recipient last updated 10/01/2013 - 1:51pm.

  10. Luis Batista, PhD

    ... shortening. Recently we developed the technology to differentiate these stem cells in a controlled, quantitative fashion, to ...

    Grant Recipient last updated 06/09/2015 - 9:22am.