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  1. Early treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion independence

    ... the impact of DMT-initiation ( azacitidine , decitabine , or lenalidomide ) timing (≤ 3 vs.>3months from start ...

    Research Article last updated 09/13/2017 - 8:58am.

  2. Comparative clinical effectiveness of azacitidine versus decitabine in older patients with myelodysplastic syndromes

    ... hypomethylating agents (HMAs) azacitidine and decitabine are both approved for treatment of myelodysplastic syndromes (MDS) in the USA. In Europe, decitabine is not approved due to lack of survival advantage in randomized ...

    Research Article last updated 10/06/2016 - 11:34am.

  3. Promising news for older AML patients

    ... untreated AML, the combination of venetoclax with either decitabine or azacitidine was associated with a 69% overall ... in Baltimore. “Venetoclax, when combined with decitabine or azacitidine, has a tolerable safety profile in treatment-naive ...

    Article last updated 07/19/2017 - 11:19am.

  4. A Phase II Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms

    ... of similar chemical or biological composition to decitabine or SGI-110. Uncontrolled intercurrent illness including, but ...

    Clinical Trial last updated 05/14/2018 - 2:02pm.

  5. A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients with Myelodysplastic Syndrome (MDS)

    ... second generation compounds such as SGI-110, oral decitabine or oral azacitidine and will also include combinations with ...

    Clinical Trial last updated 05/14/2018 - 1:57pm.

  6. Patient Trusts Her Instincts in Finding the Right Treatment

    ... .”  When I first got to CTCA, I started on decitabine (Dacogen®) using a five day/1-hour infusion.  It dropped my ...

    Patient Chronicle last updated 05/10/2018 - 11:01am.

  7. A Remarkable Response in a Clinical Trial

    ... blood cell counts. My treatment at the beginning was decitabine (Dacogen®) for 5 days every 28 days. Then after seven months, I ...

    Patient Chronicle last updated 04/26/2018 - 12:46pm.

  8. Making Progress for Myelodysplastic Syndromes

    ... medications like Vidaza ( azacitidine ), Dacogen ( decitabine ), Revlimid ( lenalidomide ). We consider transplant as a ...

    Article last updated 07/26/2017 - 10:25am.

  9. Retired MDS Patient Living Life to the Fullest Since Transplant

    ... In February 2010, I started a five-day dose of decitabine (Dacogen®) and chemotherapy and also had the first of ...

    Patient Chronicle last updated 04/26/2018 - 10:43am.

  10. Selinexor (KPT-330) in Older Patients With Relapsed/Refractory AML (SOPRA)

    ... (i) BSC alone, (ii) BSC plus either azacytidine or decitabine or (iii) BSC plus low-dose Ara-C. Overall survival is the ... Azacitidine Decitabine Selinexor (KPT-330) ...

    Clinical Trial last updated 04/17/2018 - 1:51pm.