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  1. Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation.

    ... analysis compared outcomes to that in 393 patients with de novo myelodysplastic syndrome. There was no difference in overall ...

    Research Article last updated 08/21/2014 - 9:32am.

  2. Should elderly patients with higher-risk myelodysplastic syndromes undergo allogeneic hematopoietic stem cell transplantation?

    ... stem-cell transplantation in older patients with de novo myelodysplastic syndromes : an international collaborative ...

    Research Article last updated 10/22/2013 - 3:12pm.

  3. Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia

    ... Large scale mutation profiling efforts in de novo MDS have identified mutations that correlate with clinical features ...

    Research Article last updated 02/04/2013 - 2:39pm.

  4. Paroxysmal nocturnal hemoglobinuria and pregnancy before the eculizumab era: the French experience

    ... Primary Author:  de Guibert S Author(s):  de ... cases. Two cases of severe aplastic anemia ( de novo in one case and relapse in the other) were recorded. No thrombotic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Pediatric myelodysplastic syndromes: they do exist!

    ... uncommon among pediatric hematologic malignancies, both de novo and secondary MDS occur in children and may be the first ...

    Research Article last updated 01/08/2014 - 9:02am.

  6. Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis

    ... marrow (BM) samples from 126 adult patients with de novo MDS. The results of the MS-PCR were confirmed by bisulfite sequencing. ...

    Research Article last updated 11/05/2012 - 10:10am.

  7. Monitoring of methylation changes in 9p21 region in patients with myelodysplastic syndromes and acute myeloid leukemia.

    ... Abstract Epigenetic de novo methylation of CpG islands is an important event in malignant ...

    Research Article last updated 04/26/2012 - 8:35am.

  8. Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.

    ... patients were > or = 18 years of age and had MDS ( de novo or secondary) of any French-American-British (FAB) subtype and an ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

    ... T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, Kalicki-Veizer J, ... present in 13 out of 150 (8.7%) subjects with de novo MDS, and we found suggestive evidence of an increased risk of ...

    Research Article last updated 01/09/2012 - 2:17pm.

  10. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

    ... Further explorations into the nature of chemical versus de novo disease should consider this mechanism, which is biologically ...

    Research Article last updated 04/09/2014 - 9:39am.