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  1. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... hematopoietic stem cell (HSC) disorder resulting in cytopenia . The mainstays of treatment for AA are definitive therapy to restore HSCs and supportive measures to ameliorate cytopenia-related complications. The standard definitive therapy is HSC ...

    Research Article last updated 11/01/2016 - 2:01pm.

  2. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... leukemia (AML). Anemia is the most frequent cytopenia diagnosed in patients with MDS. Regular RBC transfusions are the ...

    Research Article last updated 10/06/2016 - 1:01pm.

  3. Pediatric myelodysplastic syndromes: they do exist!

    ... group of clonal disorders characterized by peripheral cytopenia (s) and normal or hypercellular bone marrow with ... bone marrow and monosomy 7 . Refractory cytopenia is more typical than refractory anemia , as seen in the ...

    Research Article last updated 01/08/2014 - 9:02am.

  4. Diagnosis of myelodysplastic syndromes in cytopenic patients

    ... Sustained clinical cytopenia is a frequent laboratory finding in ambulatory and hospitalized ... who examine the bone marrow (BM), a diagnosis of cytopenia secondary to an infiltrative BM process or acute leukemia can be ...

    Research Article last updated 11/16/2011 - 2:20pm.

  5. The National Myelodysplastic Syndromes Natural History Study

    ... (MDS/MPN) overlap disorder, or idiopathic cytopenia of undetermined significance (ICUS).  Participants will be ... Suspected (e.g., persistent unexplained cytopenia , circulating peripheral blasts etc.) MDS or MDS/MPN ...

    Clinical Trial last updated 02/23/2017 - 1:36pm.

  6. Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study.

    ... diagnosis is not apparent; the term idiopathic cytopenia of undetermined significance (ICUS) has been used to describe ...

    Research Article last updated 09/19/2016 - 11:05am.

  7. Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts

    ... dysplasia (RARS) and 70% of those with refractory cytopenia with multilineage dysplasia and ring sideroblasts or RARS ...

    Research Article last updated 08/15/2016 - 11:29am.

  8. Anemia as the Main Manifestation of Myelodysplastic Syndromes

    ... anemia in the great majority of cases, and this cytopenia defines these pathologies and their most dramatic clinical ...

    Research Article last updated 12/02/2015 - 8:45am.

  9. Are Myelodysplastic Syndromes Underdiagnosed in Poland? A Report by the Polish Adult Leukaemia Group

    ... frequently diagnosed MDS subtype was refractory cytopenia with multilineage dysplasia (RCMD), responsible for 30.3% of all ...

    Research Article last updated 11/02/2016 - 10:17am.

  10. Aplastic Anemia & MDS International Foundation: Bone Marrow Failure Disease Scientific Symposium 2014

    ... to produce adequate blood cells, resulting in either cytopenia (defect in one or more blood cell lineages) or pancytopenia ...

    Research Article last updated 01/23/2015 - 3:36pm.