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  1. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... or immunohistochemistry within 28 days of study entry; cytogenetics , flow cytometry, and molecular studies (such as FMS-like ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  2. Pathogenesis of MDS: An overview of molecular and non-molecular aspects of the disease

    ... of prior chemotherapy or radiation.  Complex cytogenetics (3 or more abnormalities) is associated with a worse ...

    Research Review last updated 05/02/2016 - 9:14am.

  3. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... first remission (with intermediate-risk or high-risk cytogenetics including complex karyotype, abn(3q), -5/5q-, -7/7q-, ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  4. Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    ... by preceding myelodysplastic syndrome (MDS), high risk cytogenetics such as those associated with MDS or complex karyotype, > 2 ... leukemia/lymphoma: high risk CR1 as evidenced by high risk cytogenetics (e.g. t(9;22), t(1;19),t(4;11), other myeloid/lymphoid or mixed ...

    Clinical Trial last updated 05/02/2016 - 2:13pm.

  5. Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

    ... Presence of Flt3 internal tandem duplications Poor-risk cytogenetics Primary refractory disease ii. ALL (leukemia and/or lymphoma) with at least one of the following: Poor-risk cytogenetics Clear evidence of hypodiploidy Primary refractory disease iii. ...

    Clinical Trial last updated 05/02/2016 - 2:38pm.

  6. Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

    ... first remission (with intermediate-risk or high-risk cytogenetics , flt3 mutation positive and/or evidence of minimal ...

    Clinical Trial last updated 06/06/2016 - 12:58pm.

  7. Natural Killer (NK) Cells With HLA Compatible Hematopoietic Transplantation for High Risk Myeloid Malignancies

    ... the following high risk features defined as: (i) Adverse cytogenetics : -5, del 5q, -7, del7q, abnormalities involving 3q, 9q, 11q, ...

    Clinical Trial last updated 06/06/2016 - 1:18pm.

  8. Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR

    ... below: Acute myeloid leukemia with poor risk cytogenetics (1) in complete hematologic remission. These include: del ...

    Clinical Trial last updated 05/02/2016 - 11:10am.

  9. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... sub type by FAB or WHO classification; High-risk cytogenetics (eg those associated with MDS, abnormalities of 5, 7, 8, ... Any patient with newly diagnosed AML with intermediate risk cytogenetics. Any patient unable to tolerate consolidation chemotherapy as ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  10. Nursing Education Modules on MDS Disease Management and Patient Education

    ... (laboratory indices, bone marrow findings, cytogenetics ) MDS classification – FAB/WHO, IPSS, IPSS-R MDS ...

    Page last updated 04/27/2015 - 2:44pm.