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  1. Intra-Osseous Co-Transplant of UCB and hMSC

    ... (first complete remission [CR1]) with poor-risk cytogenetics or molecular markers (e.g. fms-related tyrosine kinase 3 [Flt 3] mutation , 11q23, del 5, del 7, complex cytogenetics) Second complete remission (CR2) or third complete ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  2. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... a.  18-81 years of age b.  MDS classification and cytogenetics confirmed within 8 weeks prior to or during screening as ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  3. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... to cytotoxic chemotherapy for another condition, adverse cytogenetics or complex karyotype), or any subjects > 70 years of age with ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  4. Jaroslaw Maciejewski, MD, PhD

    ... various specific aspects of stem cell biology, genetics, cytogenetics and immunobiology. Leadership ...

    Leadership Award last updated 05/02/2016 - 2:27pm.

  5. Allo HSCT Using RIC for Hematological Diseases

    ... high risk CR1 (as evidenced by preceding MDS, high risk cytogenetics , ≥ 2 cycles to obtain CR, erythroblastic or megakaryocytic ... that define high risk CR1 include but are not limited to cytogenetics demonstrating t(9;22), t (1:19), t(4;11), other MLL ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  6. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... evidenced by preceding MDS, intermediate to high risk cytogenetics , ≥ 2 cycles to obtain CR, erythroblastic or megakaryocytic ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  7. RIC Transplant Using Haplo Donors

    ... of the following: treatment-related; monosmy 7, complex cytogenetics or other high risk karyotype; IPSS score of 1.0 or greater; ... of minimal residual disease by flow cytometry , cytogenetics, or FISH Chronic Lymphocytic Leukemia/Prolymphocytic ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  8. Total Marrow Irradiation for Refractory Acute Leukemia

    ... disease (MRD) by flow cytometry , FISH or cytogenetics Myelodysplastic syndrome ≤ 55 years of age ... minimal residual disease (MRD) by flow cytometry, FISH or cytogenetics Multiple myeloma No prior autologous ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  9. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... or immunohistochemistry within 28 days of study entry; cytogenetics , flow cytometry, and molecular studies (such as FMS-like ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  10. UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    ... myelodysplastic syndromes [MDS], high risk cytogenetics such as those associated with MDS or complex karyotype, > 2 ... leukemia/lymphoma: high risk CR1 as evidenced by high risk cytogenetics (e.g. t(9;22), t(1;19),t(4;11), other mixed-lineage leukemia (MLL) ...

    Clinical Trial last updated 04/29/2016 - 10:06am.