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  1. Revised International Prognostic Scoring System (IPSS-R) for myelodysplastic syndromes

    ... a prognostic categorization model. Bone marrow cytogenetics , marrow blast percentage and cytopenias remained the basis of ...

    Research Article last updated 07/29/2014 - 8:54am.

  2. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    ... was not associated with disease status or abnormal cytogenetics . The cumulative incidence of engraftment achieved at day +30 ...

    Research Article last updated 07/28/2014 - 8:21am.

  3. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

    ... Performance status ≥ 2, intermediate- and poor-risk cytogenetics , presence of circulating blasts, and red blood cell ...

    Research Article last updated 07/28/2014 - 8:53am.

  4. Response to azacitidine is independent of p53 expression in higher-risk myelodysplastic syndromes and secondary acute myeloid leukemia.

    ... patients were p53-positive and most had very poor risk cytogenetics with chromosome 5 aberrations and monosomal karyotypes. The ...

    Research Article last updated 07/07/2014 - 9:27am.

  5. Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

    ... OS 12.4 months versus 23.7 months, p<10-4), abnormal cytogenetics (median OS 14.4 months vs 33 months, p=0.02) complex cytogenetics (median OS 12.7 months versus 23.7 months, p=0.0005), and a ...

    Research Article last updated 06/02/2014 - 11:17am.

  6. SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution

    ... counts, lower lactate dehydrogenase levels, good-risk cytogenetics and mutations of DNMT3A, but inversely related to ASXL1 ...

    Research Article last updated 04/23/2014 - 11:18am.

  7. Transplantation

     

    Page last updated 01/20/2015 - 4:45pm.

  8. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes

    ... one or more hematopoietic lineages. Classical metaphase cytogenetics and judicious use of fluorescence in situ hybridization ... appreciation that includes histomorphology, metaphase cytogenetics, and directed molecular studies. In the present health-care ...

    Research Article last updated 02/04/2014 - 2:01pm.

  9. Standardizing the Initial Evaluation for Myelodysplastic Syndromes.

    ... using laboratory results, morphology and cytogenetics . More sophisticated technologies, including multi-color ...

    Research Article last updated 11/05/2013 - 12:31pm.

  10. Cutting edge: flow cytometry in myelodysplastic syndromes

    ... syndromes (MDS), especially when cytomorphology and cytogenetics are inconclusive. Minimal requirements to analyze dysplasia ...

    Research Article last updated 08/06/2013 - 12:05pm.