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  1. Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: A report on 62 cases.

    ... showed that could be readily identified as MDS prior to cytogenetics . Fourteen percent of patients with isolated del 20q ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Transplantation for myelodysplastic syndromes 2013.

    ... relapse-free survival even in patients with high-risk cytogenetics . The optimal stem cell source may differ for different patient ...

    Research Article last updated 10/22/2013 - 12:53pm.

  3. Clinical effect of point mutations in myelodysplastic syndromes

    ... mutation, including 52% of the patients with normal cytogenetics . Mutations in RUNX1, TP53, and NRAS were most strongly ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Multiparameter flow cytometry provides independent prognostic information in patients with suspected myelodysplastic syndromes: A study on 804 patients

    ... standard diagnostic parameters cytomorphology and cytogenetics . MFC may therefore be considered an additional tool in the ...

    Research Article last updated 03/02/2015 - 1:14pm.

  5. Multicentre validation of a reproducible flow cytometric score for the diagnosis of low-risk myelodysplastic syndromes: results of a European LeukemiaNET study

    ... (P=.001), transfusion-dependency (P=.02), and poor risk- cytogenetics (P=.04). Comparable sensitivity and specificity were obtained ... syndrome, especially when morphology and cytogenetics are indeterminate. Bone Marrow ...

    Research Article last updated 06/15/2012 - 1:53pm.

  6. Who benefits from allogeneic transplantation for myelodysplastic syndromes?: new insights

    ... is mandatory and stratification according to age, cytogenetics , cytopenias, disease-related quality of life, and available ...

    Research Article last updated 01/08/2014 - 9:28am.

  7. Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.

    ... = .009), and evolution to monosomy 7 or complex cytogenetics was more common in the first quartile (18.8%; 95% CI, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... of myelodysplastic syndromes with intermediate/high-risk cytogenetics . Autologous peripheral blood stem cell transplantation does ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Types

    ... assigns patients a score based on three factors: cytogenetics (changes in cell DNA) cytopenias (low blood cell counts) ... 1.5 2 3 4 Cytogenetics Very Good   Good   ...

    Topic section last updated 11/14/2016 - 1:11pm.

  10. Specialized technique effective in identifying chromosomal abnormalities, improving prognosis for MDS

    ... on the percentage of bone marrow blasts , cytogenetics (branch of genetics which studies the chromosomes ), ... and sensitivity to degrees of cytopenias. Furthermore, cytogenetics in patients with MDS is extremely important. The current standard ...

    Research Review last updated 05/02/2016 - 9:31am.