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  1. Myelodysplastic Syndromes in Adolescent Young Adults: One Institution's Experience

    ... among patients with good, intermediate, and poor risk cytogenetics , respectively (P = .035). CONCLUSION: MDS is rare and ...

    Research Article last updated 09/19/2016 - 11:09am.

  2. Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: A report on 62 cases.

    ... showed that could be readily identified as MDS prior to cytogenetics . Fourteen percent of patients with isolated del 20q ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Transplantation for myelodysplastic syndromes 2013.

    ... relapse-free survival even in patients with high-risk cytogenetics . The optimal stem cell source may differ for different patient ...

    Research Article last updated 10/22/2013 - 12:53pm.

  4. Clinical effect of point mutations in myelodysplastic syndromes

    ... mutation, including 52% of the patients with normal cytogenetics . Mutations in RUNX1, TP53, and NRAS were most strongly ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Discontinuation of hypomethylating agent therapy in patients with myelodysplastic syndromes or acute myelogenous leukemia in complete remission or partial response: Retrospective analysis of survival after long-term follow-up

    ... (median: 4 months [95% CI: 1-8]) (p=0.043). Poor-risk cytogenetics were also associated with lower 1-year OS (33% versus 69%; ...

    Research Article last updated 05/26/2015 - 12:53pm.

  6. Multiparameter flow cytometry provides independent prognostic information in patients with suspected myelodysplastic syndromes: A study on 804 patients

    ... standard diagnostic parameters cytomorphology and cytogenetics . MFC may therefore be considered an additional tool in the ...

    Research Article last updated 03/02/2015 - 1:14pm.

  7. Multicentre validation of a reproducible flow cytometric score for the diagnosis of low-risk myelodysplastic syndromes: results of a European LeukemiaNET study

    ... (P=.001), transfusion-dependency (P=.02), and poor risk- cytogenetics (P=.04). Comparable sensitivity and specificity were obtained ... syndrome, especially when morphology and cytogenetics are indeterminate. ...

    Research Article last updated 06/15/2012 - 1:53pm.

  8. Who benefits from allogeneic transplantation for myelodysplastic syndromes?: new insights

    ... is mandatory and stratification according to age, cytogenetics , cytopenias, disease-related quality of life, and available ...

    Research Article last updated 01/08/2014 - 9:28am.

  9. Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.

    ... = .009), and evolution to monosomy 7 or complex cytogenetics was more common in the first quartile (18.8%; 95% CI, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... of myelodysplastic syndromes with intermediate/high-risk cytogenetics . Autologous peripheral blood stem cell transplantation does ...

    Research Article last updated 10/11/2011 - 5:58pm.