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  1. Serial assessment of suspected myelodysplastic syndromes: significance of flow cytometric findings validated by cytomorphology, cytogenetics, and molecular genetics

    ... in parallel by flow cytometry, cytomorphology and cytogenetics for suspected myelodysplasia without proof of myelodysplasia ... in 64/142 (45.1%) patients. In 9/142 (6.3%) patients cytogenetics revealed aberrant karyotypes at first evaluation which was true ...

    Research Article last updated 10/02/2012 - 9:48am.

  2. Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System.

    ... The IPSS gives more weight to blast count than to cytogenetics . However, previous publications suggested that cytogenetics are underweighted in the IPSS. Here we investigate the prognostic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Impact of the revised International Prognostic Scoring System cytogenetics and monosomal karyotype on outcome after allogeneic stem cell transplantation for myelodysplastic syndromes and secondary acute myeloid leukemia evolving from myelodysplastic syndr

    ... for overall survival, a model with simplified 5-group- cytogenetics (merging very good, good and intermediate cytogenetics) performed best. Furthermore, monosomal karyotype is an ...

    Research Article last updated 03/02/2015 - 2:46pm.

  4. Contribution of Revised International Prognostic Scoring System Cytogenetics to Predict Outcome After Allogeneic Stem Cell Transplantation for Myelodysplastic Syndromes: A Study From the French Society of Bone Marrow Transplantation and Cellular Therapy

    ... International Prognostic Scoring System (IPSS) cytogenetics . It has been shown that a new cytogenetic classification, ...

    Research Article last updated 04/08/2015 - 9:59am.

  5. Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations.

    ... patients with del(5q) MDS, conventional G-banding cytogenetics (CC), single nucleotide polymorphism array (SNP-A), and ...

    Research Article last updated 07/29/2014 - 8:58am.

  6. Somatic HLA mutations expose the role of class I–mediated autoimmunity in aplastic anemia and its clonal complications

    ... complications as assessed by WES, SNP-A, and metaphase cytogenetics , and more frequent secondary MDS . The finding of ...

    Research Article last updated 10/23/2017 - 10:56am.

  7. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

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    Research Article last updated 04/09/2014 - 9:39am.

  8. Cytogenetics in myelodysplastic syndromes.

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    Research Article last updated 10/11/2011 - 5:58pm.

  9. Outcome of patients treated for myelodysplastic syndromes with 5q deletion after failure of lenalidomide therapy.

    ... progression after LEN failure, and unfavorable cytogenetics . Among the treatment strategies, we observed a relatively ...

    Research Article last updated 07/11/2017 - 10:11am.

  10. Non-t(6;9) and Non-Inv(3) Balanced Chromosomal Rearrangements Are Associated With Poor Survival Outcomes in Myelodysplastic Syndromes

    ... BACKGROUND: Cytogenetics is an important predictor of survival in patients with ... overall survival (OS) similar to patients with poor risk cytogenetics, defined according to the International Prognostic Scoring ...

    Research Article last updated 06/03/2015 - 8:44am.