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  1. My Son's Aplastic Anemia -- A Mother's Account

    ... treatment in April, 2014 and stayed on a full dose of cyclosporine for 7 months, at which point he started to taper off this drug. This process took 6 months, so his cyclosporine treatment lasted 13 months. Within a few months, the ...

    Patient Chronicle last updated 12/15/2016 - 11:21am.

  2. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine has been considered the first-line therapy. Up to 80% of ...

    Interview last updated 11/28/2016 - 2:58pm.

  3. Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

    ... 14, subjects will receive hATG, Methylprednisolone and Cyclosporine . From Day 15 until Day 30 (of the first month), subjects will continue treatment only with Methylprednisolone and Cyclosporine. Cyclosporine will continue daily through Month 6/Day 30 (M6/D30) ...

    Clinical Trial last updated 04/26/2016 - 11:45am.

  4. CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

    ... normal cells (called graft-versus-host disease). Giving cyclosporine and mycophenolate mofetil after the transplant may stop this ... immune suppression therapy with either tacrolimus or cyclosporine at the time of CD8+ memory T-cell infusion; prednisone ...

    Clinical Trial last updated 04/29/2016 - 12:36pm.

  5. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

    ... to IST with horse anti-thymocyte globulin (h-ATG) and cyclosporine . Despite various efforts to improve IST results, horse ATG plus cyclosporine is still the regimen with better outcomes and is thus the standard ...

    Research Review last updated 05/02/2016 - 9:13am.

  6. Clinical Trials Report for April 2016

    ... (hATG), given in combination with methylprednisolone, cyclosporine , and G-CSF ( filgrastim or pegfilgrastim), can help to ...

    Page last updated 08/10/2016 - 11:00am.

  7. Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

    ... will receive immune modulating drugs sirolimus and cyclosporine to prevent GVHD. Objective: To determine the safety, ... that use low-intensity chemotherapy, sirolimus plus cyclosporine, and transplant booster with either Th2 cells or standard immune ...

    Clinical Trial last updated 04/28/2016 - 11:28am.

  8. Frequently Asked Questions about Aplastic Anemia

    ... effects of immunosuppressive therapy with ATG and cyclosporine ? What are the long-term and late effects of immunosuppressive therapy with ATG and cyclosporine? What other options are available if the standard approach to ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  9. Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

    ... immune response against the body's normal cells. Giving cyclosporine and mycophenolate mofetil may stop this from happening. ... Associated Drug(s):  Cyclosporine Filgrastim Fludarabine ...

    Clinical Trial last updated 04/29/2016 - 9:56am.

  10. Intra-Osseous Co-Transplant of UCB and hMSC

    ... immune response against the body's normal cells. Giving cyclosporine and mycophenolate mofetil at the time of transplant may stop ... Cyclophosphamide Cyclosporine Fludarabine Mycophenolate ...

    Clinical Trial last updated 05/02/2016 - 11:15am.