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  1. Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Hematologic Malignancies Undergoing Donor Peripheral Blood Stem Cell Transplant

    ... This phase II trial studies how well sirolimus, cyclosporine and mycophenolate mofetil works in preventing graft-vs-host ... Giving total-body irradiation together with sirolimus, cyclosporine, and mycophenolate mofetil before and after transplant may stop ...

    Clinical Trial last updated 04/28/2016 - 12:07pm.

  2. What are the side effects of cyclosporine?

    Cyclosporine is a drug that lowers your body's immune response. Cyclosporine is used along with antithymocyte globulin (ATG), another ... bone marrow failure diseases. If you are taking cyclosporine as part of your treatment regimen, your doctor should monitor you ...

    FAQ last updated 03/15/2016 - 11:48pm.

  3. Eltrombopag Added to IST Yields Encouraging Results

    ... in combination with conventional IST (horse ATG and cyclosporine ).  Eltrombopag was started two weeks after receiving ATG and starting cyclosporine to allow time to recover from the side effects of ATG. When we saw ...

    Interview last updated 05/24/2017 - 7:44am.

  4. Tyler Andrews

    ... treated. He was given the standard combination of ATG and cyclosporine, but he remembers more about his feelings than his treatment. ...

    "Like You" Patient Story last updated 08/04/2017 - 5:00pm.

  5. Ricky Smith, Jr.

    ... "With aplastic, they put me on cyclosporine , they put me on prednisone , I got the ATG shots. It ...

    "Like You" Patient Story last updated 04/05/2017 - 1:27pm.

  6. Judi Wilkinson

    ... crucial decision to remain at NIH, Judi began her ATG and cyclosporine treatment, and then had to cope with the serum sickness that ...

    "Like You" Patient Story last updated 06/01/2017 - 10:33am.

  7. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine has been considered the first-line therapy. Up to 80% of ...

    Interview last updated 11/28/2016 - 2:58pm.

  8. Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

    ... 14, subjects will receive hATG, Methylprednisolone and Cyclosporine . From Day 15 until Day 30 (of the first month), subjects will continue treatment only with Methylprednisolone and Cyclosporine. Cyclosporine will continue daily through Month 6/Day 30 (M6/D30) ...

    Clinical Trial last updated 04/26/2016 - 11:45am.

  9. CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

    ... normal cells (called graft-versus-host disease). Giving cyclosporine and mycophenolate mofetil after the transplant may stop this ... immune suppression therapy with either tacrolimus or cyclosporine at the time of CD8+ memory T-cell infusion; prednisone ...

    Clinical Trial last updated 04/29/2016 - 12:36pm.

  10. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

    ... to IST with horse anti-thymocyte globulin (h-ATG) and cyclosporine . Despite various efforts to improve IST results, horse ATG plus cyclosporine is still the regimen with better outcomes and is thus the standard ...

    Research Review last updated 05/02/2016 - 9:13am.