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  1. Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

    ... of a short course of methotrexate (MTX) combined with cyclosporine (CSP). The transplant protocol tested the hypothesis ...

    Research Article last updated 09/13/2016 - 12:50pm.

  2. Phase II study of rabbit anti-thymocyte globulin, cyclosporine and granulocyte colony-stimulating factor in patients with aplastic anemia and myelodysplastic syndrome

    ... and safety of rabbit anti-thymocyte globulin (rATG), cyclosporine and granulocyte colony-stimulating factor (G-CSF) as ... for patients >or=55 years with MDS) was given for 5 days. Cyclosporine (5 mg/kg) and G-CSF (5 microg/kg) were given daily and continued ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party

    ... (rATG; thymoglobulin, Genzyme) in combination with cyclosporine , as first-line immunosuppressive therapy, was evaluated ... registry, treated with horse ATG (hATG; lymphoglobulin) and cyclosporine. The primary end point was response at 6 months. At 3 months, no ...

    Research Article last updated 07/30/2012 - 1:51pm.

  4. Long-term outcome after immunosuppressive therapy with horse or rabbit antithymocyte globulin and cyclosporine for severe aplastic anemia in children.

    ... or rabbit antithymocyte globulin (n = 158) combined with cyclosporine as first-line therapy between 1992 and 2010. The response ...

    Research Article last updated 11/21/2013 - 11:36am.

  5. High-dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

    ... as compared with antithymocyte globulin and cyclosporine A. As children often tolerate dose-intensive therapy better ... in adults and compare favorably to antithymocyte globulin/cyclosporine A with manageable infectious toxicity. ...

    Research Article last updated 08/15/2016 - 11:49am.

  6. Simona Pagliuca, MD

    ... and immunosuppressive therapy based on two drugs: " cyclosporine " and "anti-thymoglobuline". Unfortunately not all patients are ... treatment for patients with a diagnosis of aplastic anemia? cyclosporine and anti-thymoglobuline or cyclosporine, anti-thymoglobuline + ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  7. Tyler Andrews

    ... treated. He was given the standard combination of ATG and cyclosporine, but he remembers more about his feelings than his treatment. ...

    "Like You" Patient Story last updated 08/04/2017 - 5:00pm.

  8. A Rare Case of Aplastic Anemia Later in Life Doesn’t Stop Al Meyer

    ... biopsy. In January 2012, treatment on horse ATG and cyclosporine began with encouraging results, but I had a very bad reaction (tremors) to the cyclosporine that put me back in the hospital. So ATG/cyclosporine didn’t ...

    Patient Chronicle last updated 07/12/2017 - 1:52pm.

  9. Long-term issues after Immunosuppressive therapy for Aplastic Anemia

    ... Survival rate using antithymocyte globulins and cyclosporine in patients with aplastic anemia now ranges 70-80%. ... long-term issues can be broadly divided on three topics; cyclosporine dependence, relapse of the original disease, and evolution of ...

    Research Article last updated 06/23/2016 - 8:48am.

  10. Alternative donor transplants for severe aplastic anemia: current experience

    ... therapy with anti-thymocyte globulin (ATG) and cyclosporine (CsA), or a transplant from an alternative donor. In these ...

    Research Article last updated 06/07/2016 - 10:52am.