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  1. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... immune response against the body's normal cells. Giving cyclophosphamide and fludarabine together with total-body ... Antithymocyte Globulin Cyclophosphamide Cyclosporine Fludarabine ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  2. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... intravenously (IV) over 60 minutes on days -10 to -8 and cyclophosphamide IV over 2 hours on days -3 and -2. Patients also undergo ... Associated Drug(s):  Cyclophosphamide Fludarabine Mycophenolate ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  3. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... body irradiation (TBI) on day -6. Patients also receive cyclophosphamide IV over 2 hours on days -3 and -2. TRANSPLANTATION: ... Associated Drug(s):  Cyclophosphamide Fludarabine Mycophenolate ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  4. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... using a T-cell replete allograft and post-transplant cyclophosphamide as previously described at our center (Bashey et al. J ... haploidentical transplant using post-transplant cyclophosphamide (haplo-pCy), the risk of relapse is approximately 50% at one ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  5. Allo HSCT Using RIC for Hematological Diseases

    ... This is a phase II trial using a non-myeloablative cyclophosphamide / fludarabine /total body irradiation (TBI) ... -6, -5, -4, -3 and -2 Other Name: Fludara Drug: Cyclophosphamide 50 mg/kg IV over 2 hours, day -6 Other Name: ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  6. UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    ... This is a phase II trial using a non-myeloablative cyclophosphamide / fludarabine /total body irradiation (TBI) ... 1 hour Day -6 to Day -2 Other Name: Fludara Drug: Cyclophosphamide Arm 1: 50 mg/kg IV over 2 hours Day -6 Other Name: ...

    Clinical Trial last updated 04/29/2016 - 10:06am.

  7. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... This modified regimen consists of pentostatin and oral cyclophosphamide , which we hypothesize will reduce both the T cells that ... Other endpoints include the toxicity of the pentostatin-cyclophosphamide regimen, the degree of donor-host chimerism necessary for ...

    Clinical Trial last updated 04/28/2016 - 9:09am.

  8. Pure Red Cell Aplasia (PRCA)

    ... responded to corticosteroids. Drug therapies include cyclophosphamide , cyclosporine , azathioprine with or without ...

    Topic section last updated 07/07/2016 - 3:14pm.

  9. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... patients at high risk for graft rejection that utilized cyclophosphamide , fludarabine and anti-thymocyte globulin (ATG) ...

    Clinical Trial last updated 04/25/2016 - 10:08am.

  10. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... patients at high risk for graft rejection that utilized cyclophosphamide , fludarabine and anti-thymocyte globulin (ATG) ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.