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  1. Even "Moderate" Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

    ... investigators evaluated the use of “moderate” dose cyclophosphamide for severe aplastic anemia for patients who do not have a compatible donor.  In earlier studies, high dose cyclophosphamide (200mg/kg) had unacceptable toxicities (including death from ...

    Research Review last updated 05/02/2016 - 9:23am.

  2. Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematologic Disease

    ... an umbilical cord blood transplant together with cyclophosphamide , fludarabine phosphate, and total-body irradiation ... hematologic disease. Giving chemotherapy , such as cyclophosphamide and fludarabine phosphate, and TBI before a donor umbilical ...

    Clinical Trial last updated 04/29/2016 - 1:56pm.

  3. Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

    ... when given together with fludarabine phosphate, cyclophosphamide , total-body irradiation, donor bone marrow transplant ... chemotherapy , such as fludarabine phosphate and cyclophosphamide, and total-body irradiation before a donor bone marrow ...

    Clinical Trial last updated 04/29/2016 - 12:48pm.

  4. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... and benefit of giving a type of chemotherapy - cyclophosphamide - after the transplant to prevent graft versus host ... Associated Drug(s):  Cyclophosphamide Gender:  ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  5. Improved Outcome of Reduced Toxicity Fludarabine, Cyclophosphamide Plus Thymoglobulin Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia: Comparison of Two Multicenter Prospective Studies

    ... investigators. The hope was that by reducing the dose of cyclophosphamide , increasing the dose of fludarabine , and ... The first study enrolled 28 patients who received cyclophosphamide (50mg/kg x 4 days), fludarabine (30mg/m2 for 4 days), and ...

    Research Review last updated 05/02/2016 - 9:24am.

  6. Busulfan and Cyclophosphamide Followed By ALLO BMT

    ... Antithymocyte Globulin Cyclophosphamide Cyclosporine Mycophenolate ... guidelines. Other Name: Myleran Drug: Cyclophosphamide Days -3 and -2 (prior to transplantation): given as a 2 ...

    Clinical Trial last updated 04/29/2016 - 1:23pm.

  7. Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

    ... Associated Drug(s):  Cyclophosphamide Fludarabine Mycophenolate ... dose is 1 mg IV QD. Other Names: Fludara Cyclophosphamide TBI High-dose Cy MMF Tacrolimus ...

    Clinical Trial last updated 05/02/2016 - 2:38pm.

  8. Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

    ... JMML can be achieved with a treatment of busulfan (BU), cyclophosphamide (CY) and melphalan (L-PAM) followed by hematopoietic cell ... Associated Drug(s):  Cyclophosphamide Phase:  ...

    Clinical Trial last updated 07/14/2016 - 3:59pm.

  9. Clinical Trials Report for April 2016

    ... Study Coordinator Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis The main purpose of this study is to assess the effects of cyclophosphamide (cytoxan) in the post transplant setting to prevent onset of ...

    Page last updated 08/10/2016 - 11:00am.

  10. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... and the best dose of genetically modified T-cells after cyclophosphamide in treating patients with relapsed or refractory ... Associated Drug(s):  Cyclophosphamide Fludarabine ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.