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  1. Evaluation of efficacy of alemtuzumab in 5 patients with aplastic anemia and/or myelodysplastic neoplasm

    ... paroxysmal nocturnal hemoglobinuria (PNH) clone was detected before therapy. One responder relapsed after 15 months ... a subset of patients with MDS, even in the presence of a PNH clone. Bone Marrow Diseases:  ...

    Research Article last updated 11/01/2016 - 1:56pm.

  2. Performance characteristics of consensus approaches for small and minor paroxysmal nocturnal hemoglobinuria clone determination by flow cytometry.

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    Research Article last updated 07/09/2013 - 3:33pm.

  3. Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

    ... resolution for paroxysmal nocturnal hemoglobinuria clone detection. Bone Marrow Diseases:  ...

    Research Article last updated 11/02/2016 - 10:42am.

  4. Paroxysmal Nocturnal Hemoglobinuria (PNH)

    ... PNH red blood cells. Doctors also call them your PNH clone . The PNH red blood cells lack the shield of proteins that protect ...

    Page last updated 09/30/2017 - 11:34am.

  5. Fighting PNH While Helping PNH Patients

    ... and have been on it ever since. I have a significant PNH clone , but the drug is working well. So it’s under control for the most ...

    Patient Chronicle last updated 11/21/2016 - 12:47pm.

  6. Clone of Clone of Caring for Yourself

    ...

    Page last updated 04/11/2016 - 12:34pm.

  7. Multiparameter FLAER-based flow cytometry for screening of paroxysmal nocturnal hemoglobinuria enhances detection rates in patients with aplastic anemia

    ... detection of paroxysmal nocturnal hemoglobinuria (PNH) clone . This study aimed to compare PNH clone detection by flow cytometry in the pre-FLAER era versus the FLAER era. ...

    Research Article last updated 01/20/2015 - 2:45pm.

  8. Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria

    ... anemia . PNH results from expansion of a clone of hematopoietic cells that, as a consequence of an inactivating ... proteins CD55 and CD59, the red cells arising from this clone are exquisitely sensitive to lysis by activated complement. Until a ...

    Research Article last updated 06/07/2016 - 10:56am.

  9. Clonal hematopoiesis in acquired aplastic anemia

    ... and PIGA mutations tend to disappear or show stable clone size and predict significantly better response to IST and clinical ... ASXL1, and other genes, which are likely to increase their clone size and associated with a faster progression to MDS/AML and predict an ...

    Research Article last updated 06/22/2016 - 10:18am.

  10. Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion

    ... recurrent somatic mutations identified in the diseased clone on response to lenalidomide and the drug effects on clonal evolution ...

    Research Article last updated 04/29/2016 - 11:33am.