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  1. An update on the treatment of myelodysplastic syndromes.

    ... , are approved for intermediate-2- and high-risk MDS. Trial results have increased the understanding of these treatments, alone or ... often requires at least three to six months to achieve a clinical response. In the meantime, or in addition to active therapy, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes.

    ... BACKGROUND: In the AZA-001 trial, azacitidine (75 mg/m(2)/d subcutaneously for Days 1-7 of every ... category in 48% of patients, and therefore may enhance clinical benefit in patients with higher-risk MDS. ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.

    ... Decitabine given on a 5-day schedule provided meaningful clinical benefit for patients with MDS, with more than half demonstrating ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... enrollment on this protocol may be abandoned if the clinical situation dictates an urgent transplant in the best medical judgment ...

    Clinical Trial last updated 05/22/2017 - 11:00am.

  5. AAMDSIF Summer Fellowship Grant Program

    ... MD. at tWashington University, St. Louis, as part of a clinical research team on MDS. Rigoberto investigated DNA response to two ... samples from 6 patients enrolled on the ongoing clinical trial , for whom response data was available. Three non-responders who ...

    Page last updated 05/17/2017 - 1:29pm.

  6. Eltrombopag Added to IST Yields Encouraging Results

    ... data on self-reported health outcomes play in evaluating a trial like this? With improved blood counts and lessened need for ... of their quality of life improved right along with their clinical outcomes. What are they key points for newly diagnosed and longer ...

    Interview last updated 05/24/2017 - 7:44am.

  7. A Phase 2 Safety and Efficacy Study of RA101495 to Treat PNH Patients Who Have an Inadequate Response to Eculizumab

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... the efficacy, appropriateness or suitability of any clinical trial listed on this website. Pharmaceutical company sponsored ...

    Clinical Trial last updated 04/20/2017 - 11:14am.

  8. MEDALIST Trial

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is a Phase ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  9. Finding a Trial

    ... Finding a Clinical Trial If you are considering joining a clinical trial, the first step is ...

    Page last updated 01/20/2015 - 4:59pm.

  10. Finding a Trial

    ... Finding a Clinical Trial If you are considering joining a clinical trial, the first step is ...

    Page last updated 01/20/2015 - 4:47pm.