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  1. NHLBI profiles a member of the Foundation’s patient community.

    ... of Health (NIH), asking if she could be a part of the trial. She learned that to be eligible, she first needed to be a ... as much about their disease as possible — as well as about clinical trials being conducted at the National Institutes of Health.” ...

    Article last updated 06/13/2016 - 1:51pm.

  2. Simona Pagliuca, MD

    ... A and anti-thymoglobuline. In 2014 the experimental trial named RACE has been started in Europe trying to improve the results of ... research concerns the biological part arising from this clinical trial : we are trying to characterize the immunological aberration ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  3. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... with the drug for years. In our aplastic anemia trial several patients have been on the drug for over two years. Is ... MDS. Do you have a timeline for the Phase 3 clinical trial period and how soon Eltrombopag could be possibly be ...

    Interview last updated 07/06/2012 - 3:42pm.

  4. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... hematopoietic responses were observed in a recent clinical trial using eltrombopag in patients with severe aplastic anemia refractory ...

    Research Article last updated 06/20/2013 - 10:13am.

  5. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... enrollment on this protocol may be abandoned if the clinical situation dictates an urgent transplant in the best medical judgment ...

    Clinical Trial last updated 05/22/2017 - 11:00am.

  6. Oral Azacitidine (CC-486) for the Treatment of Myelodysplastic Syndromes and Acute Myeloid Leukemia

    ... with >30% blasts have also been shown in a recent phase III trial. Oral administration of azacitidine may enhance patient convenience, ... oral azacitidine (CC-486) have shown biological activity, clinical responses, and tolerability in patients with MDS and AML. Extended ...

    Research Article last updated 12/09/2015 - 8:49am.

  7. AAMDSIF Summer Fellowship Grant Program

    ... MD. at tWashington University, St. Louis, as part of a clinical research team on MDS. Rigoberto investigated DNA response to two ... samples from 6 patients enrolled on the ongoing clinical trial , for whom response data was available. Three non-responders who ...

    Page last updated 05/17/2017 - 1:29pm.

  8. Platelet count doubling after the first cycle of azacitidine therapy predicts eventual response and survival in patients with myelodysplastic syndromes and oligoblastic acute myeloid leukaemia but does not add to prognostic utility of the revised IPSS

    ... 4, 2014 Reliable clinical or molecular predictors of benefit from azacitidine therapy ... whose data was collected in a prospective clinical trial with a longer median follow-up. We found a significant association ...

    Research Article last updated 08/04/2014 - 8:37am.

  9. 5-Azacytidine in myelodysplastic syndromes: a clinical practice guideline.

    ... the treatment or management of MDS. Of those, six clinical articles of prospective phase 2-3 study design or meta-analyses were ... agents at this time outside the context of a clinical trial . Bone Marrow Diseases:  ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Eltrombopag Added to IST Yields Encouraging Results

    ... data on self-reported health outcomes play in evaluating a trial like this? With improved blood counts and lessened need for ... of their quality of life improved right along with their clinical outcomes. What are they key points for newly diagnosed and longer ...

    Interview last updated 05/24/2017 - 7:44am.