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  1. Research Retrospective for AA&MDSIF 30th Anniversary - Dr. Neal Young

    ... often do not realize that treatments are established in clinical protocols. When I ask an audience of hundreds of patients how many are in a clinical trial , one or two raise a hand! So patients want the information, but they ...

    Interview last updated 05/08/2013 - 2:51pm.

  2. Interviews with the Experts Comorbidities: When Other Medical Conditions Affect MDS Treatment

    ... The severity of comorbid conditions is also relevant to clinical trials. Most trials of new drugs are trying to enroll a healthier ... one of the study participants has a bad event while on the trial due to a comorbid condition, it could be erroneously blamed on the drug ...

    Interview last updated 11/17/2014 - 9:31am.

  3. Interviews with the Experts Pioneering Quality of Life Research for MDS Patients

    ... issues, to name a few. In discussing these issues with my clinical mentors, we thought it would be important to measure MDS-related ... observation was that around 40% of patients on the NIH trial who were refractory to immunosuppression did have a response to ...

    Interview last updated 04/03/2014 - 2:13pm.

  4. Resistance to Hypomethylating Agents in the Treatment of MDS

    ... to 60% to 80% overall response rates for MDS patients in clinical trials. But that still means about 25% or more patients are ... .  And for other patients, enrolling onto a clinical trial is available to them and offers a therapy that they would not ...

    Interview last updated 06/17/2014 - 9:15am.

  5. Casey O’Connell, MD

    ... University of Southern California (USC). In addition to her clinical work with patients at the Norris Comprehensive Cancer Center, she ... clinical trials, the most exciting of which is a Phase I trial utilizing a novel hypomethylating agent for patients with MDS and acute ...

    Page last updated 04/18/2012 - 1:47pm.

  6. Ramon V. Tiu, MD

    ... A total of four patients were successfully enrolled in this trial. All four patients had refractory aplastic anemia. None of the patients ... single nucleotide polymorphism arrays, especially in their clinical application in myeloid malignancies like myelodysplastic ...

    Grant Recipient last updated 10/30/2012 - 6:28pm.

  7. Lower-Risk MDS: Diagnosis and Treatment Options

    ... will be considered. It is also important in designing clinical trials and applying the results of clinical trials. We do not take data from a trial involving lower-risk patients and apply them to higher-risk patients, ...

    Interview last updated 05/18/2012 - 1:28pm.

  8. Tips for Managing Fatigue in Bone Marrow Failure Diseases

    ... the most evidence and are category 1 recommendations (NCCN Clinical Practice Guidelines in Oncology:Cancer-Related Fatigue). ... (a high level of evidence from a randomized, controlled trial). Antidepressants should be considered only if depression is present ...

    Interview last updated 05/18/2012 - 2:20pm.