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  1. Shirley O’Brien’s Remarkable Response in a Clinical Trial

    ... I had only a few months to live unless I found a clinical trial and soon. Neither of the two oncologists offered to help me find a ...

    Patient Chronicle last updated 07/19/2017 - 8:12am.

  2. Taming the nausea, vomiting caused by chemo

    ... , according to results from a large NCI-funded phase III clinical trial . Patients in the trial were being treated with chemotherapy ...

    Article last updated 08/11/2016 - 3:27pm.

  3. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... modifier azacitidine . In an expanded phase 1 trial, CC-486 demonstrated clinical and biological activity in patients with International Prognostic ...

    Research Article last updated 06/23/2016 - 10:17am.

  4. Major news in BMT with half-match donors

    ... and the primary investigator of many UT Southwestern clinical trials related to bone marrow transplantation. Mr. Dandridge enrolled in one such UT Southwestern clinical trial , studying a therapy called AG-221, developed by Agios Pharmaceuticals ...

    Article last updated 06/14/2016 - 3:02pm.

  5. Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion

    ... MDS patients randomized in the GFM-Len-Epo2008 clinical trial to lenalidomide or lenalidomide + EPO. Clonal evolution was analyzed ...

    Research Article last updated 04/29/2016 - 11:33am.

  6. Self-injected PNH therapy on the horizon

    ... positive interim data from the first cohort in its phase Ib trial that show maintenance of complement inhibition using Coversin in healthy ... diseases, and Alexion presented the first clinical data for its own next-generation complement inhibitors. Overall, we ...

    Article last updated 07/07/2016 - 9:40am.

  7. Personalized medicine for MDS

    ... in myelodysplastic syndromes: wishful thinking or already clinical reality? Original Publication Date:  ... approach, however, has not been tested in a clinical trial .  -One personalized approach for lower-risk patients with MDS is ...

    Research Review last updated 05/02/2016 - 9:44am.

  8. NHLBI profiles a member of the Foundation’s patient community.

    ... of Health (NIH), asking if she could be a part of the trial. She learned that to be eligible, she first needed to be a ... as much about their disease as possible — as well as about clinical trials being conducted at the National Institutes of Health.” ...

    Article last updated 06/13/2016 - 1:51pm.

  9. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... with the drug for years. In our aplastic anemia trial several patients have been on the drug for over two years. Is ... MDS. Do you have a timeline for the Phase 3 clinical trial period and how soon Eltrombopag could be possibly be ...

    Interview last updated 07/06/2012 - 3:42pm.

  10. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... hematopoietic responses were observed in a recent clinical trial using eltrombopag in patients with severe aplastic anemia refractory ...

    Research Article last updated 06/20/2013 - 10:13am.