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  1. Gemtuzumab Receives New FDA Approval for Acute Myeloid Leukemia

    ... initially successful treatment. However, confirmatory clinical trials showed that the drug did not improve survival and was linked ... of the toxic payload into the cells. In the clinical trial that led to the new approval of gemtuzumab as part of induction ...

    Research Article last updated 10/03/2017 - 12:56pm.

  2. A Rare Case of Aplastic Anemia Later in Life Won't Stop Me

    ... had no response to.  So in late 2013, they put me in a clinical trial for eltrombopag, which I had already tried once before, but this is ...

    Patient Chronicle last updated 04/26/2018 - 10:42am.

  3. FDA approves first drug to treat GVHD

    ... The agency’s approval was based on a nonrandomized clinical trial in which nearly half of patients treated with ibrutinib had significant ...

    Article last updated 08/29/2017 - 7:55am.

  4. Foundation Update - September 2017

    ... leukemia, ibrutinib's approval came after a randomized clinical trial in which almost half the participants treated with the drug showed a ...

    Article last updated 09/12/2017 - 7:14am.

  5. A call for action: Increasing enrollment of untreated patients with higher-risk myelodysplastic syndromes in first-line clinical trials.

    ... azacitidine , prolonged survival in a large randomized trial. However, multiple real-life and registry analyses have demonstrated ... not been replicated in population-based studies or in other clinical trials using azacitidine monotherapy arms. Herein, we critically ...

    Research Article last updated 09/11/2017 - 9:04am.

  6. A Phase 2 Study of Tipifarnib in Subjects with Chronic Myelomonocytic Leukemia

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... the efficacy, appropriateness or suitability of any clinical trial listed on this website. Pharmaceutical company sponsored ...

    Clinical Trial last updated 04/23/2018 - 2:51pm.

  7. A Phase 1b/2 Study to Evaluate the Safety and Efficacy of APR-246 in Combination with Azacitidine for the Treatment of TP53 Mutant Myeloid Neoplasms

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... the efficacy, appropriateness or suitability of any clinical trial listed on this website. Pharmaceutical company sponsored ...

    Clinical Trial last updated 04/21/2018 - 6:04pm.

  8. Selinexor (KPT-330) in Older Patients With Relapsed/Refractory AML (SOPRA)

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... the efficacy, appropriateness or suitability of any clinical trial listed on this website. Pharmaceutical company sponsored ...

    Clinical Trial last updated 04/17/2018 - 1:51pm.

  9. Foundation Update - August 2017

    ... ongoing story – including the particulars of this clinical trial and his family's support, all as parts of his experience in this ...

    Article last updated 09/05/2017 - 10:53am.

  10. FDA approves new drug for relapsed or refractory AML

    ... (NCT01915498), an open-label, single-arm, multicenter, clinical trial of enasidenib that included 199 adults with relapsed or refractory ...

    Article last updated 08/30/2017 - 8:30am.