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  1. Foundation Update - September 2017

    ... leukemia, ibrutinib's approval came after a randomized clinical trial in which almost half the participants treated with the drug showed a ...

    Article last updated 09/12/2017 - 7:14am.

  2. A call for action: Increasing enrollment of untreated patients with higher-risk myelodysplastic syndromes in first-line clinical trials.

    ... azacitidine , prolonged survival in a large randomized trial. However, multiple real-life and registry analyses have demonstrated ... not been replicated in population-based studies or in other clinical trials using azacitidine monotherapy arms. Herein, we critically ...

    Research Article last updated 09/11/2017 - 9:04am.

  3. FDA approves first drug to treat GVHD

    ... The agency’s approval was based on a nonrandomized clinical trial in which nearly half of patients treated with ibrutinib had significant ...

    Article last updated 08/29/2017 - 7:55am.

  4. Foundation Update - August 2017

    ... ongoing story – including the particulars of this clinical trial and his family's support, all as parts of his experience in this ...

    Article last updated 09/05/2017 - 10:53am.

  5. Jill Minden’s Encounter with Aplastic Anemia

    ... once again. They sent me to the NIH for a clinical trial of eltrombopag, which after a number of trips back and forth from my ...

    Patient Chronicle last updated 09/05/2017 - 10:57am.

  6. FDA approves new drug for relapsed or refractory AML

    ... (NCT01915498), an open-label, single-arm, multicenter, clinical trial of enasidenib that included 199 adults with relapsed or refractory ...

    Article last updated 08/30/2017 - 8:30am.

  7. New study on SCT therapy for SAA, MDS patients

    ... The study is being led by Dr Richard W Childs, Clinical Director of the National Heart, Lung, and Blood Institute’s (NDLBI) ... exciting prior data, we are now conducting a clinical trial at the NHLBI testing whether umbilical cord blood transplantation ...

    Article last updated 08/22/2017 - 9:41am.

  8. Senior citizens underrepresented in clinical trials

    ... Article Link:  Seniors Miss Out On Clinical Trials Article Source:  ... 75 or older, only 4 percent of breast cancer clinical trial participants are of this age. - Although 33 percent of colon cancer ...

    Article last updated 06/29/2017 - 10:44am.

  9. PACCT+ Patient Group Meets and Learns Together

    ... On June 17, the AAMDSIF Patient Advisory Council on Clinical Trials (PACCT+) members met in Arlington, Virginia for the second ... members and learning from two experts about clinical trial design and the state of current MDS research. By their selection and ...

    Article last updated 07/10/2017 - 11:12am.

  10. An exploratory clinical trial of bortezomib in patients with lower risk myelodysplastic syndromes

    ... Bortezomib is safe in this patient population but has modest clinical activity. The role of the proteasome in the genesis of ring ...

    Research Article last updated 05/02/2017 - 10:33am.