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  1. Myelodysplastic Syndromes and Acute Myeloid Leukemia in the Elderly

    ... can influence life expectancy and treatment tolerance. Clinical trials accounting for the heterogeneity of tumor biology and ... with MDS and AML and highlights future directions for research. Bone Marrow Diseases:  ...

    Research Article last updated 12/09/2015 - 1:30pm.

  2. Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?

    ... The current prognostic tools sum the impact of clinical, pathologic, and laboratory parameters. Newer technologies with ... mutational data into daily clinical practice and how future research could help improve the prognostication precision and specific therapy ...

    Research Article last updated 09/28/2015 - 9:48am.

  3. MDS Clinical Research Consortium Meets at ASH 2016

    ... (ASH) meeting kicked in, AAMDSIF and members of the MDS Clinical Research Consortium (MDS CRC) took the opportunity to meet with partners ...

    Article last updated 12/14/2016 - 12:37pm.

  4. Accuracy of physician assessment of treatment preferences and health status in elderly patients with higher-risk myelodysplastic syndromes.

    ... Survey tools included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC ... attitude toward a lower degree of patient involvement in clinical decisions. Agreement on health status was found in 27.5% of cases. ...

    Research Article last updated 09/15/2015 - 10:09am.

  5. Simona Pagliuca, MD

    ... on immune derangements of aplastic anemia: (translational) research from the randomized EBMT race study Original ... research concerns the biological part arising from this clinical trial : we are trying to characterize the immunological aberration ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  6. Paroxysmal Nocturnal Hemoglobinuria: A Complement-Mediated Hemolytic Anemia

    ... largely mediated by the alternative pathway of complement. Clinical manifestations result from the lack of specific cell surface ... Complement inhibition strategies are an area of active research. Bone Marrow Diseases:  ...

    Research Article last updated 06/23/2015 - 9:32am.

  7. Genetics factors associated with myelodysplastic syndromes

    ... miR-125a and MiR-21. Somatic mutations may influence the clinical phenotype but are not included in current prognostic scoring systems. In recent years research has brought new insights into these diseases, but few of the findings ...

    Research Article last updated 06/03/2015 - 11:30am.

  8. Genome sequencing in myelodysplastic syndromes: can molecular mutations predict benefit from hypomethylating agent therapy?

    ... many patients do not derive benefit. There is an urgent clinical need to identify patients with low probability of benefiting from ... therapies in patients with MDS remains a top clinical and a research priority. Bone Marrow Diseases:  ...

    Research Article last updated 03/03/2015 - 1:03pm.

  9. AAMDSIF Summer Fellowship Grant Program

    ... MD, of Baylor College of Medicine. She describes her research project: Low-risk myelodysplasia (LR-MDS) is a group of disorders ... MD. at tWashington University, St. Louis, as part of a clinical research team on MDS. Rigoberto investigated DNA response to two ...

    Page last updated 05/17/2017 - 1:29pm.

  10. Cutting the cord from myelodysplastic syndromes: chronic myelomonocytic leukemia-specific biology and management strategies

    ... recognized as a distinct entity with unique biologic and clinical features. This change has created a scientific and clinical research landscape that makes it difficult to discern CMML-specific validated ...

    Research Article last updated 03/02/2015 - 1:22pm.