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  1. Optimization of therapy for severe aplastic anemia based on clinical, biologic, and treatment response parameters: conclusions of an international working group on severe aplastic anemia convened by the Blood and Marrow Transplant Clinical Trials Network.

    ... To address this issue, the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) convened a group of international experts in ... and propose initiatives to facilitate clinical and biologic research. Key conclusions of the working group were: (1) new patients should ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Platelet count doubling after the first cycle of azacitidine therapy predicts eventual response and survival in patients with myelodysplastic syndromes and oligoblastic acute myeloid leukaemia but does not add to prognostic utility of the revised IPSS

    ... Reliable clinical or molecular predictors of benefit from azacitidine therapy ... azacitidine therapy remains an unmet medical need and a top research priority. Bone Marrow ...

    Research Article last updated 08/04/2014 - 8:37am.

  3. Danielle Townsley, MD, MSc

    ... the National Heart Lung and Blood Institute (NHLBI) at the Clinical Center of the National Institutes of Health in Bethesda, Maryland. She ... and Phillip Scheinberg. Currently she conducts her research in the laboratory of Dr. Neal Young, Chief of the Hematology Branch of ...

    Bio last updated 05/24/2017 - 8:30am.

  4. Myelodysplastic Syndromes and Acute Myeloid Leukemia in the Elderly

    ... can influence life expectancy and treatment tolerance. Clinical trials accounting for the heterogeneity of tumor biology and ... with MDS and AML and highlights future directions for research. Bone Marrow ...

    Research Article last updated 12/09/2015 - 1:30pm.

  5. Eltrombopag Added to IST Yields Encouraging Results

    ... better. We do this with well-validated surveys in medical research and included these surveys in this study. Not many studies of aplastic ... of their quality of life improved right along with their clinical outcomes. What are they key points for newly diagnosed and longer ...

    Interview last updated 05/24/2017 - 7:44am.

  6. Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?

    ... The current prognostic tools sum the impact of clinical, pathologic, and laboratory parameters. Newer technologies with ... mutational data into daily clinical practice and how future research could help improve the prognostication precision and specific therapy ...

    Research Article last updated 09/28/2015 - 9:48am.

  7. Optimizing management of myelodysplastic syndromes post-allogeneic transplantation

    ... preemptive therapy is an important goal of current clinical research . Further strategies aiming at an improved prevention of ...

    Research Article last updated 12/05/2011 - 10:23am.

  8. Allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndromes

    ... to prevent relapse, is an important goal of current clinical research . There is an urgent need for prospective randomized trials to ...

    Research Article last updated 11/05/2012 - 9:30am.

  9. Accuracy of physician assessment of treatment preferences and health status in elderly patients with higher-risk myelodysplastic syndromes.

    ... Survey tools included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC ... attitude toward a lower degree of patient involvement in clinical decisions. Agreement on health status was found in 27.5% of cases. ...

    Research Article last updated 09/15/2015 - 10:09am.

  10. Treatments

    ...   Clinical Trials Clinical research is at the heart of all medical advances, identifying new ways to ...

    Topic section last updated 02/16/2017 - 3:04pm.