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  1. The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes.

    ... conditions and, to some extent, appear to define distinct clinical phenotypes in MDS. The high frequency of mutations in different ... targets of the spliceosome mutations is an active area of research. Emerging data from the study of the MDS transcriptome suggests that ...

    Research Article last updated 10/22/2013 - 3:41pm.

  2. Overview of myelodysplastic syndromes

    ... by diagnostic entities of world renown as well as by other research groups and individuals to establish a reliable prognostic system. ... subgroups and the role of molecular markers in predicting clinical evolution. Bone Marrow Diseases:  ...

    Research Article last updated 11/05/2012 - 9:53am.

  3. Genetics of myelodysplastic syndromes: new insights

    ... contribute to disease pathogenesis is an active area of research, with a current focus on which downstream target genes may be ... are sufficiently robust to be incorporated into routine clinical practice at this time. Additional studies will be required to ...

    Research Article last updated 01/09/2012 - 2:04pm.

  4. Optimizing hypomethylating agents in myelodysplastic syndromes

    ... will hopefully be modified with future results of ongoing clinical and translational research. Bone Marrow Diseases:  ...

    Research Article last updated 04/26/2012 - 8:31am.

  5. Horse versus rabbit antithymocyte globulin in acquired aplastic anemia

    ... peripheral-blood lymphocytes and is preferred in other clinical circumstances. METHODS: From December 2005 through July ... response and survival. (Funded by the Intramural Research Program of the National Institutes of Health; ClinicalTrials.gov ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Consideration B

    ... Clinical Research Educational Site Clinical research studies can offer good ...

    Page last updated 03/14/2016 - 10:23am.

  7. Consideration A

    ... Clinical Research Educational Site Clinical research studies can offer good ...

    Page last updated 03/14/2016 - 10:20am.

  8. Professionals

    ... and their families. MDS Clinical Research Consortium AAMDSIF ...

    Page last updated 01/18/2017 - 9:52am.

  9. MDS and Inflammation

    ... for this. What are some possible directions for future research? I think the most important take home message is that ... as a pill. These agents have been licensed to Celgene for clinical development in the years ahead. In the laboratory they work ... of lenalidomide (Revlimid®) from the laboratory to clinical trials, which went on to receive fast-track designation from the U.S. ...

    Interview last updated 02/14/2017 - 8:52am.

  10. More Information

    ... What are the different types of clinical trials? Treatment trials test new treatment options. For ... to take part in all the phases. The early phases of a research study make sure the drug or treatment is safe. The later phases of ...

    Page last updated 01/20/2015 - 4:59pm.