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  1. Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation

    ... by the International Prognostic Scoring System Chronic myelogenous leukemia (CML) in accelerated or second chronic phase ... of GvHD or GvL. Must not have uncontrolled intercurrent illness including ongoing or active infection, symptomatic congestive heart ...

    Clinical Trial last updated 05/02/2016 - 2:07pm.

  2. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... high risk include pre-existing conditions such as a chronic disease affecting kidneys, liver, lungs, or heart or previous failed ... virus (HIV) seropositivity Severe psychological illness such as major psychosis (e.g. schizophrenia), major bipolar depression, ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  3. FAQs

    ... What are the treatments for PNH? PNH is considered chronic. That means it lasts for a long time. The only known cure is a bone ... trials to improve the comfort of people with chronic illness Prevention trials to look for better ways to prevent disease in ...

    Topic section last updated 03/02/2016 - 11:42am.

  4. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... ≥ 70% One of the following high-risk malignancies: Chronic Myelogenous Leukemia (chronic phase, resistant and/or intolerant to ... Patients who have any debilitating medical or psychiatric illness which would preclude their giving informed consent or their receiving ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  5. Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

    ... Life expectancy is not severely limited by concomitant illness Adequate cardiac and pulmonary function; patients with decreased ... on protocol after discussion with the PI No evidence of chronic active hepatitis or cirrhosis Human immunodeficiency virus ...

    Clinical Trial last updated 05/23/2016 - 2:06pm.

  6. Intra-Osseous Co-Transplant of UCB and hMSC

    ... (including non-Hodgkin lymphoma, Hodgkin lymphoma and chronic lymphocytic leukemia) meeting the following criteria: Disease ... fraction < 35% Patients with uncontrolled inter-current illness including, but not limited to ongoing or active infection, symptomatic ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  7. Clinical Trial Basics

    ... the comfort and quality of life for patients with a chronic illness through supportive care . What are some risks of being in a ...

    Page last updated 01/20/2015 - 4:58pm.

  8. Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

    ... blasts in the bone marrow ) or patients with Chronic Myelomonocytic Leukemia (CMML) (having >/= 10% blasts in the bone ... medical condition, laboratory abnormality, or psychiatric illness, which could place him/her at unacceptable risk. Patients who have ...

    Clinical Trial last updated 05/23/2016 - 3:37pm.

  9. Clinical Trial Basics

    ... the comfort and quality of life for patients with a chronic illness through supportive care . What are some risks of being in a ...

    Page last updated 01/20/2015 - 4:46pm.

  10. PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation (FLUBUTBI)

    ... Diagnosis of acute myelogenous leukemia , chronic myelogenous leukemia, other myeloproliferative disorder, or ... <70% Life expectancy limited by another co-morbid illness Diagnosed or treated for another malignancy within 3 years of ...

    Clinical Trial last updated 04/29/2016 - 3:09pm.