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  1. Transplants in Myelodysplastic Syndromes

    ... of de novo but also of secondary forms after prior chemotherapy or radiotherapy, respectively, is anticipated within the next ...

    Research Article last updated 01/20/2015 - 1:10pm.

  2. Jill Whitney – Since my diagnosis, my mission has been to fight back

    ... not even recovered from my transplant and was now facing chemotherapy . I began receiving azacitidine (Vidaza®), but my ... of my stem cell transplant (re-birthday). I tolerate chemotherapy pretty well now and take medication to mitigate the side effects. ...

    Patient Chronicle last updated 05/26/2015 - 9:29am.

  3. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... of the enzymes needed for cell growth. Drugs used in chemotherapy , such as azacitidine , work in different ways to stop ... untreated AML, if not candidates for standard induction chemotherapy or with poor risk AML (i.e. preceding MDS, myeloproliferative ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  4. Lack of objective response of myelodysplastic syndromes and acute myeloid leukemia to decitabine after failure of azacitidine

    ... leukemia (AML) unlikely to benefit from cytotoxic chemotherapy . Switching hypomethylating agents after treatment failure is ...

    Research Article last updated 10/02/2014 - 10:13am.

  5. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... patients with these diseases can be treated with medical chemotherapy alone. However, patients who relapse following chemotherapy are usually not curable with additional chemotherapy treatments. ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  6. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... high risk acute myeloid leukemia. Giving low doses of chemotherapy before a donor peripheral blood stem cell transplant ... to administration of 1st dose of remission induction chemotherapy ; if a bone marrow aspirate and biopsy were obtained within 28 ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  7. Update on the pharmacotherapy for myelodysplastic syndromes

    ... relied upon supportive care and intensive chemotherapy . The last decade has seen many scientific and therapeutic ...

    Research Article last updated 08/21/2014 - 9:23am.

  8. Myelodysplastic syndromes

    ... in a third of patients. 15% of cases occur after chemotherapy or radiotherapy for a previous cancer; the syndromes are most ...

    Research Article last updated 04/16/2014 - 12:04pm.

  9. Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update

    ... Due to their lower toxicity compared to conventional chemotherapy , hypomethylating agents are often a safe and feasible ... may play a role in epigenetic "priming" before conventional chemotherapy. This review summarizes the results of clinical trials and ...

    Research Article last updated 11/05/2012 - 9:34am.

  10. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... to replace blood-forming cells that were destroyed by chemotherapy and radiation therapy, or that have become cancer. Sometimes ... clinical trial is studying how well giving combination chemotherapy together with radiation therapy followed by cyclosporine and ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.