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  1. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... myeloproliferative disorders (MPD). Giving low doses of chemotherapy , such as fludarabine phosphate, and total-body irradiation ... transplant helps stop the growth of cancer cells. Giving chemotherapy or radiation therapy before or after transplant also stops the ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  2. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... peripheral blood stem cell transplant . Giving chemotherapy and total-body irradiation before a donor peripheral blood ... RAEB-2) (if the patient has received previous induction chemotherapy within 60 days) Chronic myelogenous leukemia with a ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  3. Rasha Iqbal's Transplant Experience Amplifies Her Desire for Research Career

    ... mother and I headed to Duke where I received intensive chemotherapy followed by bone marrow harvested from my loving brother. I ... Still, I had many struggles due to the months of not eating, chemotherapy, immunosuppressive medication, and inadequate exercise as both my ...

    Patient Chronicle last updated 11/13/2015 - 11:27am.

  4. 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... previous treatment ( refractory ). Drugs used in chemotherapy , such as 8-chloro-adenosine, work in different ways to stop ... who have failed hypomethylating agent or induction chemotherapy Patients who have relapsed after allogeneic hematopoietic ...

    Clinical Trial last updated 05/23/2016 - 3:25pm.

  5. Treatment of Higher-Risk Myelodysplastic Syndromes After Failure of Hypomethylating Agents

    ... use of HMAs, add-back strategies, other palliative chemotherapy options, and provide an overview for several promising ...

    Research Article last updated 09/29/2015 - 2:12pm.

  6. Dr. Kasiani Myers: Acquired and Inheirited Bone Marrow Failure

    ... and has been functionally destroyed. We do use chemotherapy for both categories of aplastic anemia, but the type and strength of this chemotherapy is often very different. The majority of inherited marrow failures ...

    Interview last updated 02/14/2017 - 8:34am.

  7. MDS - Treatment (OLD)

    ... can lower your body's immune response Chemotherapy , using drugs that kill abnormal cells Bone marrow ... Chemotherapy The risk of developing ...

    Topic section last updated 03/10/2016 - 11:01pm.

  8. Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy.

    ... syndromes in complete remission (CR) after induction chemotherapy . Sixty patients were enrolled and treated by standard induction chemotherapy. Patients that reached CR started maintenance therapy with ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... of the enzymes needed for cell growth. Drugs used in chemotherapy , such as azacitidine , work in different ways to stop ... untreated AML, if not candidates for standard induction chemotherapy or with poor risk AML (i.e. preceding MDS, myeloproliferative ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  10. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... high risk acute myeloid leukemia. Giving low doses of chemotherapy before a donor peripheral blood stem cell transplant ... to administration of 1st dose of remission induction chemotherapy ; if a bone marrow aspirate and biopsy were obtained within 28 ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.