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  1. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ... have achieved at least partial response following additional chemotherapy. Patients with high risk cytogenetics at diagnosis ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  2. Myelodysplastic syndromes: What do hospitalists need to know?

    ... with MDS develop the disorder as a result of previous chemotherapy or radiation as treatment for another malignancy.  There are ... (Vidaza®) and decitabine (Dacogen®), intensive chemotherapy, and stem cell transplantation.  Patients tend to tolerate ...

    Research Review last updated 05/02/2016 - 9:21am.

  3. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... blast crisis in 2nd chronic phase following induction chemotherapy ) Acute Myelogenous Leukemia (2nd or subsequent complete remission [CR] (OR) Primary induction chemotherapy failure, but subsequently entered into a CR(OR) 1st CR with poor ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  4. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... metastases and did not achieve a CR with surgery and/or chemotherapy Karnofsky (patients > 16 years) or Lansky (patients ... have fully recovered from acute toxic effects of all prior chemotherapy, immunotherapy, or radiotherapy prior to entering this study ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  5. MDS Patient Becomes a Role Model

    ... in my mother’s footsteps, in November of 2013 I had chemotherapy and radiation followed by a bone marrow transplant from an ... in my feet (tingling, pain, numbness or weakness) from the chemotherapy, radiation, and all of the medication I had to take for the ...

    Patient Chronicle last updated 04/22/2016 - 5:19pm.

  6. Options for MDS patients beyond HMAs

    ... including:  low dose cytarabine; aggressive chemotherapy ; switching to the other of the two HMAs – preferably ...

    Research Review last updated 05/02/2016 - 9:09am.

  7. Lukasz Gondek, M.D., Ph.D.

    ... cells self-renewal, proliferation, and resistance to chemotherapy . Results of this study may contribute to more accurate ...

    Bio last updated 03/11/2016 - 1:41pm.

  8. SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)

    ... significant toxicities Grade ≥2 from previous chemotherapy not readily controlled by supportive measures (excluding ... nausea, and fatigue) Patient has received treatment with chemotherapy, wide-field radiation, or biologic therapy within 14 days of study ...

    Clinical Trial last updated 06/06/2016 - 2:11pm.

  9. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  10. What are the treatments for MDS?

    ... (Dacogen) and azacitidine (Vidaza). Chemotherapy :  Treats MDS by using drugs that kill abnormal cells. ...

    FAQ last updated 03/15/2016 - 11:31pm.