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  1. A Phase II Study of 5-Azacitidine and Sargramostim as Maintenance Treatment After Definitive Therapy for Poor-risk AML or MDS

    ... cell transplant or cytarabine-based consolidation chemotherapy . In order to precede relapse and to avoid lead time bias, ...

    Clinical Trial last updated 05/03/2016 - 10:38am.

  2. Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

    ... with hematological malignancies. Giving low doses of chemotherapy , such as fludarabine phosphate, before a donor PBSC ...

    Clinical Trial last updated 05/03/2016 - 9:44am.

  3. Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS (AML)

    ... refractory AML after treatment failure of up to 1 prior chemotherapy regimen (Arm B). ...

    Clinical Trial last updated 05/02/2016 - 11:06am.

  4. Eltrombopag in aplastic anemia

    ... (BMT), providing immunosuppression (through high dose chemotherapy ) plus healthy hematopoietic progenitor cells; or with ...

    Research Review last updated 05/02/2016 - 9:13am.

  5. Safety and Tolerability of HSC835 in Patients With Hematological Malignancies

    ... (HIV) infection Active infection Extensive prior chemotherapy Prior myeloablative allotransplantation or autologous ...

    Clinical Trial last updated 04/29/2016 - 2:14pm.

  6. Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematologic Disease

    ... in treating patients with hematologic disease. Giving chemotherapy , such as cyclophosphamide and fludarabine phosphate, and TBI ...

    Clinical Trial last updated 04/29/2016 - 1:56pm.

  7. Filgrastim, Cladribine, Cytarabine and Mitoxantrone With or Without Sorafenib Tosylate in Treating Patients With Newly-Diagnosed, High-Risk Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... likely to come back or spread (high-risk). Drugs used in chemotherapy , such as filgrastim, cladribine, cytarabine, and mitoxantrone ...

    Clinical Trial last updated 04/29/2016 - 1:03pm.

  8. Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

    ... in treating patients with hematologic cancer. Giving chemotherapy , such as fludarabine phosphate and cyclophosphamide, and ...

    Clinical Trial last updated 04/29/2016 - 12:48pm.

  9. Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

    ... cancer to grow, which commonly do not respond to regular chemotherapy . Status:  ...

    Clinical Trial last updated 04/29/2016 - 10:38am.

  10. Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Complete Remission (QUAZAR AML-001)

    ... (CRi) following induction with or without consolidation chemotherapy . Subjects who have previously achieved CR/CRi with a ...

    Clinical Trial last updated 04/29/2016 - 8:39am.