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  1. Factors affecting response to treatment for secondary MDS and AML

    ... increases in patients who receive multiple rounds of chemotherapy and radiation therapy, and also in those who undergo stem cell ... included surgery (1252 patients), radiation (939 patients), chemotherapy (1211 patients), or observation (124 patients).  Patients whose ...

    Research Review last updated 05/02/2016 - 9:32am.

  2. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  3. Allo HSCT Using RIC for Hematological Diseases

    ... in marrow after having failed one or more cycles of chemotherapy . Acute Lymphocytic Leukemia (ALL): factor that define high ... mass greater than 5 cm) should be considered for de-bulking chemotherapy before transplant. Lymphoplasmacytic Lymphoma, Mantle-Cell ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  4. A Study of E6201 for the Treatment of Advanced Hematologic Malignancies With FLT3 Mutation (AML)

    ... FLT3+ AML and not eligible for standard induction chemotherapy or FLT3+ high-risk MDS/CMML (defined as ≥ 10% ... to prior therapy At least 4 weeks beyond the last chemotherapy, (or ≥ 2 weeks or ≥ 2 5 half- lives for targeted agents, ...

    Clinical Trial last updated 05/09/2016 - 4:09pm.

  5. Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery

    ... but not limited to biological therapy, radiotherapy, chemotherapy , or surgical procedures. Any other surgery (except biopsies) ... agent while on study. Patients who have received chemotherapy or radiotherapy within 4 weeks prior to entering the study or ...

    Clinical Trial last updated 04/28/2016 - 1:57pm.

  6. Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive Chemotherapy

    ... after they are discharged from the hospital following chemotherapy . After treatment and hospital discharge, patients typically need extensive care to deal with the side effects of chemotherapy, keep up with medications, and obtain medical assistance. A home ...

    Clinical Trial last updated 04/29/2016 - 12:50pm.

  7. Risk of developing MDS and AML after radiation treatment for breast cancer

    ... increases in patients who receive multiple rounds of chemotherapy and radiation therapy, and also in those who undergo stem cell ... lymphoma. Read more about t-MDS Radiation and chemotherapy are key components of cancer treatments and carry an increased ...

    Research Review last updated 05/02/2016 - 9:32am.

  8. Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

    ... newly diagnosed acute myeloid leukemia. Drugs used in chemotherapy , such as clofarabine, daunorubicin hydrochloride, cytarabine, ... them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which ...

    Clinical Trial last updated 04/28/2016 - 12:10pm.

  9. Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

    ... that can be given safely when it is combined with two chemotherapy drugs ( fludarabine and cytarabine). This study will be ... participant's best interest based on disease progression. Chemotherapy may be delayed by 1-3 days if clinically indicated. Other ...

    Clinical Trial last updated 04/28/2016 - 9:48am.

  10. Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders (BMT)

    ... Traditionally, very strong cancer treatment drugs ( chemotherapy ) and radiation are used to prepare a subject's body for ... attack the recipient's normal body. Recently, less intense chemotherapy and radiation regimens have been employed (these are called ...

    Clinical Trial last updated 04/27/2016 - 1:04pm.