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  1. Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

    ... 2 weeks have elapsed since prior systemic cytotoxic chemotherapy (except intrathecal chemotherapy, hydroxyurea, low-dose cytarabine, and/or low dose maintenance ...

    Clinical Trial last updated 06/06/2016 - 10:04am.

  2. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... own immune system is prevented by giving low doses of chemotherapy ( fludarabine phosphate and cyclophosphamide) and ... remission (CR) High-risk MDS status-post cytotoxic chemotherapy Burkitt's lymphoma: second or subsequent CR ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  3. Fatigue in Bone Marrow Failure Diseases

    ... tell what the source of the fatigue is? For example, are chemotherapy , radiation and stem cell transplants all suspect, along with ... had different kinds of previous treatments – radiation, chemotherapy, stem cell transplants among them – tend to have more fatigue. ...

    Interview last updated 01/06/2017 - 2:22pm.

  4. MEDALIST Trial

    ... as the result of chemical injury or treatment with chemotherapy and/or radiation for other diseases. Known clinically ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  5. Acute Myeloid Leukemia (AML)

    ... and myelodysplastic syndromes (MDS) Previous chemotherapy or radiation treatments for other cancers ... use several types of therapy for adults with AML: Chemotherapy or other drug therapies are the first line of treatment. ...

    Topic section last updated 07/07/2016 - 3:15pm.

  6. Adoptive Transfer of Haplo-identical DLI for AML and MDS

    ... The primary hypothesis is that chemotherapy followed by donor lymphocyte infusion (DLI) from ... of elderly patients with high-risk AML or MDS compared to chemotherapy alone, and that that this benefit will be even greater in ...

    Clinical Trial last updated 05/03/2016 - 9:59am.

  7. Preventing Stem Cell Transplant Complications With a Blood Separator Machine

    ... the stem cells. Recipients will have radiation and chemotherapy to prepare for the stem cell transplant. They will then have ... anemia (less than or equal to 10g/dl) not due to recent chemotherapy . OR 5.1.2.7 Non-Hodgkin s lymphoma including Mantle cell ...

    Clinical Trial last updated 05/23/2016 - 10:57am.

  8. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... that have not achieved a CR after 2 cycles of induction chemotherapy ; for patients with AML evolving from myelodysplastic syndrome, they should have at least one cycle of induction chemotherapy Research participants must have bone marrow and ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  9. MDS Drug Therapy

    ... conventional care, including supportive care and chemotherapy . They found that about 5 in 10 patients had some positive ... regimens, including best supportive care and chemotherapy . In this study about 3 in 10 patients had a positive response, ...

    Topic section last updated 03/10/2016 - 11:26pm.

  10. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ... NHL in remission which is considered not curable with chemotherapy alone and not eligible/appropriate for autologous transplant. ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.