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  1. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... peripheral blood stem cell transplant . Giving chemotherapy and total-body irradiation before a donor peripheral blood ... RAEB-2) (if the patient has received previous induction chemotherapy within 60 days) Chronic myelogenous leukemia with a ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  2. MDS - Treatment (OLD)

    ... can lower your body's immune response Chemotherapy , using drugs that kill abnormal cells Bone marrow ... Chemotherapy The risk of developing ...

    Topic section last updated 03/10/2016 - 11:01pm.

  3. 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... previous treatment ( refractory ). Drugs used in chemotherapy , such as 8-chloro-adenosine, work in different ways to stop ... who have failed hypomethylating agent or induction chemotherapy Patients who have relapsed after allogeneic hematopoietic ...

    Clinical Trial last updated 05/23/2016 - 3:25pm.

  4. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... T cells still present and then about 4 days later giving chemotherapy to kill these T cells. The approach we studied involved using ... half- matched transplant, including the lack of any need for chemotherapy after a haplo transplant. With those types of transplants, there ...

    Interview last updated 10/04/2017 - 1:36pm.

  5. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... patients with these diseases can be treated with medical chemotherapy alone. However, patients who relapse following chemotherapy are usually not curable with additional chemotherapy treatments. ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  6. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... of the enzymes needed for cell growth. Drugs used in chemotherapy , such as azacitidine , work in different ways to stop ... untreated AML, if not candidates for standard induction chemotherapy or with poor risk AML (i.e. preceding MDS, myeloproliferative ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  7. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... to replace blood-forming cells that were destroyed by chemotherapy and radiation therapy, or that have become cancer. Sometimes ... clinical trial is studying how well giving combination chemotherapy together with radiation therapy followed by cyclosporine and ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  8. Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    ... RATIONALE: Drugs used in chemotherapy , such as fludarabine and cyclophosphamide , ... able to replace blood-forming cells that were destroyed by chemotherapy and radiation therapy. Sometimes the transplanted cells from a ...

    Clinical Trial last updated 05/02/2016 - 2:13pm.

  9. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... high risk acute myeloid leukemia. Giving low doses of chemotherapy before a donor peripheral blood stem cell transplant ... to administration of 1st dose of remission induction chemotherapy ; if a bone marrow aspirate and biopsy were obtained within 28 ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  10. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    For more details on this clinical trial, including contact information, please see this trial’s listing on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT02143830 ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.