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  1. STAT3-mutations indicate the presence of subclinical T cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

    ... a STAT3 mutant clone showed lower degree of BM cellularity and a higher frequency of developing chromosome 7 ...

    Research Article last updated 07/29/2014 - 11:59am.

  2. The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes.

    ... Histological examination revealed a comparable BM cellularity and BM blast percentage, but markedly increased megakaryocytes ...

    Research Article last updated 06/20/2013 - 11:02am.

  3. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... Aplastic Anemia (SAA), with bone marrow cellularity of <25% OR Severe Isolated Single Lineage Cytopenia and ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  4. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... light microscopy within the bone marrow with a cellularity of ≥15%. Acute lymphocytic leukemia - high risk CR1 ... <5% blasts by light microscopy within the bone marrow with a cellularity of ≥15%. Chronic myelogenous leukemia all types except blast ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  5. Eltrombopag in aplastic anemia

    ... showed trilineage responses. An increase in bone marrow cellularity was seen in several responders. Six patients who achieved ... and all maintained stable blood counts and normal marrow cellularity after a median of 24 months off drug. Considering these ...

    Research Review last updated 05/02/2016 - 9:13am.

  6. Allo HSCT Using RIC for Hematological Diseases

    ... light microscopy within the bone marrow with a cellularity of ≥15%. Very high risk pediatric patients with AML: ... <5% blasts by light microscopy within the bone marrow with a cellularity of ≥15%. Very high risk pediatric patients with ALL: patients ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  7. North American Pediatric Aplastic Anemia Consortium Symposium

    ... from other diseases causing markedly decreased marrow cellularity primarily by evaluation of the bone marrow.  Expert ... classification.  The criteria for SAA excluded any patchy cellularity, particularly of erythroid lineage and did not allow any ...

    Page last updated 10/31/2013 - 4:06pm.

  8. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... reticulocyte count ≤ 1%, and Bone marrow cellularity ≤ 25%, or bone marrow cellularity ≤ 50% with fewer than 30% hematopoietic cell, Hepatic: alanine ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  9. Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

    ... with SLL, CLL, or PLL, < 20% of bone marrow cellularity involved by this process (to lower risk of graft rejection). ...

    Clinical Trial last updated 05/02/2016 - 2:38pm.

  10. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... (e.g., Auer rods) in a bone marrow with > 20% cellularity , peripheral blood counts showing ANC > 1000/ul, including ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.