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  1. Optimization of therapy for severe aplastic anemia based on clinical, biologic, and treatment response parameters: conclusions of an international working group on severe aplastic anemia convened by the Blood and Marrow Transplant Clinical Trials Network.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... the basic science, immunosuppressive therapy (IST), and bone marrow transplantation (BMT) of SAA and propose initiatives to ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Aplastic Anemia: Alternative Immunosuppressive Treatments and Eltrombopag. A report from the 2014 EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties

    ... AA is the most typical form of immune-mediated bone marrow failure; the standard treatment of AA for patients who lack a transplant option is immunosuppressive treatment (IST). The standard IST ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Aplastic anemia: pathophysiology and treatment.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... poor outcome in older patients. The lack of a suitable bone marrow donor for all patients who need a transplant, illustrates the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... in a fludarabine -based conditioning regimen for bone marrow transplantation from unrelated donors in patients with severe ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... (SAA). We studied 1204 recipients of HLA-matched sibling bone marrow transplantation for SAA to determine whether HLA DR15 status ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Hematopoietic stem cell transplantation in children and young adults with secondary myelodysplastic syndrome and acute myeloid leukemia following aplastic anemia

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... 4.4 to 26.7 years), patients underwent HSCT with bone marrow (n = 6) or peripheral blood stem cell (n = 11) grafts from ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... colony-stimulating factor (G-CSF)-primed bone marrow and G-CSF-mobilized peripheral blood stem cells of haploidentical ... (500 mg/m2·d)+anti-human thymocyte IgG. Transplant recipients also received cyclosporin A, mycophenolatemofetil, and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Outcome of Aplastic Anemia in adolescence. A survey of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation

    ... Anemia Working Party of the European Group for Blood and Marrow Transplantation comparing (i) matched family donor hematopoietic stem ... hematopoietic stem cell transplantation using bone marrow cells is the first choice treatment. If such a donor is not ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes

    ... However, for patients with a high blast count (>5 % of bone marrow at the time of diagnosis), pre-transplant HMA therapy had a NRM ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

    ... Journal Title:  Bone Marrow Transplant Primary Author:  ...

    Research Article last updated 07/20/2018 - 5:15pm.