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  1. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... (HSC) and mesenchymal stem cells (MSC) affected graft failure and graft-versus-host disease (GVHD) in patients with severe ... colony-stimulating factor (G-CSF)-primed bone marrow and G-CSF-mobilized peripheral blood stem cells of haploidentical ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... areas of general consensus, including the need for a bone marrow evaluation, cytogenetic and specific fluorescent in situ ... to IST, the time after IST initiation defining a treatment failure; use of hematopoietic growth factors; the preferred rescue therapy ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Prognostic value of telomere attrition in patients with aplastic anemia.

    ... possible mechanistic insight into genomic instability of bone marrow cells derived from patients with critically short telomeres and/or ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Aplastic anemia: pathophysiology and treatment.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... poor outcome in older patients. The lack of a suitable bone marrow donor for all patients who need a transplant, illustrates the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. The search for better prognostic models in myelodysplastic syndromes.

    ... syndromes (MDS) are a group of heterogeneous bone marrow disorders characterized by a failure of hematopoiesis and ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. A closer look at paroxysmal nocturnal hemoglobinuria

    ... intravascular hemolysis , hypercoagulablilty, and bone marrow failure result in a wide range of clinical sequlae. Although ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Horse versus rabbit antithymocyte globulin in acquired aplastic anemia

    ... failure is the result of immune-mediated destruction of bone marrow stem and progenitor cells. Immunosuppressive therapy with ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Outcome of Aplastic Anemia in adolescence. A survey of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation

    ... Anemia Working Party of the European Group for Blood and Marrow Transplantation comparing (i) matched family donor hematopoietic stem ... hematopoietic stem cell transplantation using bone marrow cells is the first choice treatment. If such a donor is not ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Cerebral venous thrombosis in paroxysmal nocturnal hemoglobinuria: a series of 15 cases and review of the literature

    ... stem cells characterized by hemolytic anemia , marrow failure, and a high incidence of life-threatening venous thrombosis ... 50% at 6 years, occurring in patients that did not have bone marrow transplantation or eculizumab therapy. Cases of death ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Allogeneic transplantation for aplastic anemia

    ... transplantation is important regardless of donor type; bone marrow is the preferred graft. ...

    Research Article last updated 07/20/2018 - 5:14pm.