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  1. Foundation Update - August 2017

    ... research on telomere length in childhood bone marrow failure . He has now been awarded a Department of Defense grant to ...

    Article last updated 09/05/2017 - 10:53am.

  2. Foundation Update - September 2017

    ... to increasing research and public education for bone marrow failure disease. The Council is comprised of individuals who have ...

    Article last updated 09/12/2017 - 7:14am.

  3. The microenvironment in myelodysplastic syndromes: niche-mediated disease initiation and progression

    ... cells and represent the most common cause of acquired marrow failure. Hallmarked by ineffective hematopoiesis , dysplastic ... of MDS pathogenesis, evidence now identify the bone marrow microenvironment (BMME) as another key contributor to disease ...

    Research Article last updated 09/13/2017 - 8:25am.

  4. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... IST regimens (i.e. with/without G-CSF or eltrombopag). While marrow cellularity did not correlate with peripheral-blood counts at 3 ... indices. Covert dysplasia, identified through early bone marrow assessment, has implications on future therapy choices after ...

    Research Article last updated 09/13/2017 - 7:40am.

  5. Progress in Myelodysplastic Syndromes: Clinicopathologic Correlations and Immune Checkpoints

    ... with immune checkpoint PD-1 inhibitor. RESULTS: Bone marrow (BM) morphology, differential counts and aberrant flow markers were ...

    Research Article last updated 09/11/2017 - 8:59am.

  6. New study on SCT therapy for SAA, MDS patients

    ... the drug. Severe AA is a condition in which the bone marrow does not produce enough blood cells for the body, and hypoplastic ...

    Article last updated 08/22/2017 - 9:41am.

  7. Top honor goes to AAMDSIF Medical Advisor

    ... to novel treatment paradigms in myelodysplasia and bone marrow failure disorders, and will impact a much broader range of diseases ...

    Article last updated 08/29/2017 - 7:54am.

  8. Outcome of patients treated for myelodysplastic syndromes with 5q deletion after failure of lenalidomide therapy.

    ... a negative impact on survival of advanced age, higher bone marrow blast count at LEN initiation, progression after LEN failure, and ...

    Research Article last updated 07/11/2017 - 10:11am.

  9. T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

    ... characterized by intravascular hemolysis , bone marrow (BM) failure, and venous thrombosis . The etiology of ...

    Research Article last updated 07/27/2017 - 2:06pm.

  10. Outcomes and healthcare utilization in children and young adults with aplastic anemia: A multiinstitutional analysis

    ... BACKGROUND: Aplastic anemia is a bone marrow failure syndrome with high mortality affecting children and young ...

    Research Article last updated 07/18/2017 - 10:32am.