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  1. Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria

    ... PNH were either supportive treatment - often including blood transfusion , anti- thrombosis prophylaxis, and sometimes ...

    Research Article last updated 06/07/2016 - 10:56am.

  2. Blood Transfusions

    Blood Transfusions A transfusion usually involves only certain parts of blood. These might be the red blood cells, platelets or plasma . Rarely ...

    Topic section last updated 03/29/2016 - 7:17pm.

  3. Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

    ... endogenous erythropoietin levels and limited red blood cell transfusion history can predict response to erythropoiesis-stimulating agents ... Variables including baseline endogenous THPO levels, transfusion needs, and platelet response were analysed in a randomized trial ...

    Research Article last updated 08/04/2014 - 8:33am.

  4. Personalized medicine for MDS

    ... patients into “lower-risk” disease, where improvement in blood counts is the main goal of therapy, and “higher-risk” disease, where ... agents (ESAs) as a single agent reduces transfusion dependence in about 50% of lower-risk MDS patients.  However, no ...

    Research Review last updated 05/02/2016 - 9:44am.

  5. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... the response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal Nocturnal ...

    Research Article last updated 09/26/2013 - 3:28pm.

  6. The immunomodulatory agents lenalidomide and thalidomide for treatment of the myelodysplastic syndromes: A clinical practice guideline.

    ... with the aging population. Treatment includes red blood cell transfusion for anemia . The immunomodulatory agents (imids) ...

    Research Article last updated 10/01/2012 - 10:04am.

  7. A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

    Journal Title:  Blood Primary Author:  Fenaux P ... the efficacy and safety of lenalidomide in 205 RBC transfusion-dependent patients with IPSS Low-/Intermediate-1-risk del5q31 ...

    Research Article last updated 07/28/2014 - 9:04am.

  8. Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes

    ... Overall Response (complete or partial remission, red blood cell [RBC] or platelet transfusion independence [TI], or hematologic improvement, (IWG 2006) was ...

    Research Article last updated 12/09/2015 - 8:56am.

  9. Brittany Springer – Aplastic Anemia Patient “Just Focused on Beating It”

    ... due to my work and school schedule. She ran a regular CBC blood test.  The next day,  I was surprised to see I had missed a call ... she thought I might have leukemia. She told me I needed a transfusion (my platelet count was 56). I was so upset I could not ...

    Patient Chronicle last updated 04/29/2016 - 3:29pm.

  10. Blood stream infection after stem cell transplantation in children with idiopathic aplastic anemia

    Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... transplantation from unrelated donors, frequent blood transfusion before transplantation, major or major+minor mismatch of ABO ...

    Research Article last updated 04/23/2014 - 10:34am.